Does testosteron have an effect on bone mineral density in postmenopausal women?

Dilek Arpaci; Fatma Saglam; Neslihan Cuhaci; Reyhan Ersoy; Bekir Cakir

doi:10.1530/endoabs.35.P78

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Endocrine Abstracts (2014) 35 P78 | DOI: 10.1530/endoabs.35.P78

ECE2014 Poster Presentations Bone and Osteoporosis (36 abstracts)

Does testosteron have an effect on bone mineral density in postmenopausal women?

Dilek Arpaci ¹ , Fatma Saglam ² , Neslihan Cuhaci ² , Reyhan Ersoy ² & Bekir Cakir ²

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¹Department of Endocrinology, Sakarya Education and Research Hospital, Sakarya, Turkey; ²Department of Endocrinology and Metabolism, Ankara Ataturk Education and Research Hospital, Ankara, Turkey.

Background: Osteoporosis is a common problem in postmenoausal women. There is limited data about the physiological importance of endogenous testosterone on bone mineral density (BMD) in older women is poorly understood.

Aim: The aim of this study was to evaluate association of endogeneous testosterone with BMD and BMI.

Materials-methods: This cross-sectional study included 64 patients (45–85 year) postmenopausal women; their demographic features, BMD and serum total testosteron levels and relationship between testosterone and BMD were evaluated. When the patients divided into three cathegories according to BMD; Group 1A: normal; Group 1B:osteopenic; Group 1C:osteoporotic.

Results: Serum total testosterone levels were found not to be correlated with BMD. We didn’t find any differences in serum testosterone levels between three BMD groups.

Conclusion: This study suggests that endogenous androgens are influential on bone density in postmenopausal women. However, we didn’t find any relationship. Effects of endogenous testosterone level on BMD is controversial.