ECE2014 Poster Presentations Bone and Osteoporosis (36 abstracts)
Does testosteron have an effect on bone mineral density in postmenopausal women?
Dilek Arpaci 1 , Fatma Saglam 2 , Neslihan Cuhaci 2 , Reyhan Ersoy 2 & Bekir Cakir 2
1Department of Endocrinology, Sakarya Education and Research Hospital, Sakarya, Turkey; 2Department of Endocrinology and Metabolism, Ankara Ataturk Education and Research Hospital, Ankara, Turkey.
Background: Osteoporosis is a common problem in postmenoausal women. There is limited data about the physiological importance of endogenous testosterone on bone mineral density (BMD) in older women is poorly understood.
Aim: The aim of this study was to evaluate association of endogeneous testosterone with BMD and BMI.
Materials-methods: This cross-sectional study included 64 patients (45–85 year) postmenopausal women; their demographic features, BMD and serum total testosteron levels and relationship between testosterone and BMD were evaluated. When the patients divided into three cathegories according to BMD; Group 1A: normal; Group 1B:osteopenic; Group 1C:osteoporotic.
Results: Serum total testosterone levels were found not to be correlated with BMD. We didn’t find any differences in serum testosterone levels between three BMD groups.
Conclusion: This study suggests that endogenous androgens are influential on bone density in postmenopausal women. However, we didn’t find any relationship. Effects of endogenous testosterone level on BMD is controversial.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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