ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2014) 35 P137 | DOI: 10.1530/endoabs.35.P137

Effects of nutritional intervention program on vitamin D serum levels in adolecents

M Mar Campos Pastor1, Ma Dolores Serrano Pardo2, Ma Luisa Fernández Soto1, Juan de Dios Luna del Castillo3, Fernando Escobar Gómez-Villalba1 & Fernando Escobar-Jiménez1


1Endocrinology and Nutrition Unit, University Hospital San Cecilio, Granada, Spain; 2Andalussian Healthy Service, Granada, Spain; 3Department of Biostatistics, School of Medicine, Granada, Spain.


Introduction: Vitamin D deficiency and insufficiency is highly prevalent even in young people. Vitamin D status has been linked to the BMI and insulin resistance.

Aim: Determine 25(OH)D concentrations in adolescents before and after nutritional intervention program (NIP) and its relationship to BMI and metabolic syndrome (MS).

Methods: We selected 256 secondary school students (127 males) aged between 12 and 16 years from Granada (Spain), who were followed-up throughout one school year. In September and May it was determined 25(OH)D, food consumption frequency and both anthropometric and biochemical profile. The NIP comprised a class on nutritional and lifestyle recommendations for adolescents to achieve adequate growth, limiting TV/computer use substituted by outdoor activity and physically active, every 15 days and daily breakfast in school composed of a diary product rich in vitamin D, fruit, cereals, nuts, and sandwich with protein content.

Results: Preintervention, 18.7% of adolescents present vitamin D deficiency, 7.4% present a several deficiency, and 38.2% present insufficiency. After the NIP, the prevalence of deficiency was reduced to 0.46% (P<0.0001) and insufficiency was reduced to 19.1% (P<0.0001). The NIP effects depends on the BMI (P<0.006), fat mass (P<0.05), consumption of linolenic acid (P<0.03), and plama cholesterol (P<0.02).

Conclusion: The NIP has a powerful effect on vitamin D status, correcting the deficiency and reducing significantly the prevalence of insufficiency.

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