ECE2014 Poster Presentations Endocrine tumours and neoplasia (99 abstracts)
Adrenal incidentaloma: is it a disease of elderly? A clinical study of 2650 cases registered at a single endocrinological center
Anna Kasperlik-Załuska 1 , Maciej Otto 2 , Andrzej Cichocki 3 , Rafał Słapa 4 , Katarzyna Rozkowszka 5 , Janina Słowińska-Srzednicka 1 , Elżbieta Rosłonowska 1 , Wojciech Jeske 1 , Piotr Zdunowski 1 & Wojciech Zgliczyński 1
1Departmant of Endocrinology, Medical Center of Postgraduate Education, Warsaw, Poland; 2Department of General, Vascular and Transplant Surgery, Medical University of Warsaw, Warsaw, Poland; 3Department of Surgery, Maria-Skłodowska-Curie Institute of Oncology, Warsaw, Poland; 4Diagnostic Imaging Department, Medical University of Warsaw, Warsaw, Poland; 5Department of Patomprphology, Maria Skłodowska-Curie Institute of Oncology, Warsaw, Poland.
It is generally believed that frequency of incidentally found adrenal tumours (adrenal incidentaloma(AI)) increases with age. Our study aimed at an analysis of age patterns in our group of patients with AI.
Design: Material: 2650 patients, 1943 womens, 707 men. The diagnostic basis: clinical examination, imaging studies, hormonal determinations, pathomorphological and cytochemical investigations of the surgically removed 755 adrenal tumours. The material has been divided into three groups: i) probably benign tumours – 2363; ii) adrenal carcinoma – 192; iii) metastatic tumours – 62 patients, in three subsets – up to 30 years old, 30–60 and over 60 years of age. A group of 17 patients with other malignant tumours did not change the statistics.
Results: In the total population we found 107 patients up to 30 years old (4%), group 1 – 73=3%, group 2 – 33=17%, and group 3 – 0. Patients ranging 31 – 60 years of age: group 1 –1278=54%, group 2 – 113=59%, group 3 – 28=47%. The patients aged over 60 years: group 1 – 1012=43%, group 2 – 46=24%, group 3 – 33=53%.
Conclusions: i) Only in patients with metastatic tumours a prevalence of patients over 60 years of age was noted. ii) In the most numerous group, including benign tumours patients aged 31–60 years dominated iii) Interestingly, there were 4% of young patients, up to 30 years of age, in the total group of AI, the most frequently in the ACC group (17%), exceeding the data from the literature. iv) In the total group of 2650 cases, 31–60 years old patients dominated over other age compartments; thus adrenal incidentaloma is a disease of mainly middle-aged patients.
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