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Endocrine Abstracts

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17th European Congress of Endocrinology

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Calcium, Vitamin D and Bone (1)

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Calcium, Vitamin D and Bone
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Diabetes and obesity – Translational diabetes

ea0037gp.11.01 | Calcium, Vitamin D and Bone (1) | ECE2015

Abstract withdrawn....
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ea0037gp.11.02 | Calcium, Vitamin D and Bone (1) | ECE2015

Hypocalcaemia development in patients operated for primary hyperparathyroidism: can it be predicted preoperatively?

Kaya Cafer , Tam Abbas Ali , Dirikoc Ahmet , Kiliyazgan Aylin , Kilic Mehmet , Turkolmez Ceyda , Ersoy Reyhan , Cakir Bekir

Introduction: Primary hyperparathyroidism (PHP) is a highly prevalent disease, which is treated most effectively by surgery. Postoperative hypocalcaemia, a morbidity of surgical treatment of parathyroidism, can prolong the hospital stay. The aim of this study was to identify the factors predictive of hypocalcaemia and hungry bone syndrome (HBS) in patients who undergo parathyroidectomy due to PHP.Materials and methods: Preoperatively and on days 1 and 4,...
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ea0037gp.11.03 | Calcium, Vitamin D and Bone (1) | ECE2015

The evaluation of central corneal and retinal thickness and intraocular pressure in patients with primary hyperparathyroidism

Baser Husniye , Cuhaci Fatma Neslihan , Topaloglu Oya , Yulek Fatma , Ugurlu Nagihan , Ersoy Reyhan , Cagil Nurullah , Cakir Bekir

Introduction: Ocular changes are common in various endocrine disorders. However, there are only few studies reporting ocular changes in patients with primary hyperparathyroidism (PHPT). Here, we examined central corneal thickness (CCT) and retinal thickness (RT), intraocular pressure (IOP) and their relationships with serum intact parathyroid hormone (iPTH), calcium (Ca), and phosphorus levels in PHPT patients.Methods: Thirty-seven patients with PHPT wer...
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ea0037gp.11.04 | Calcium, Vitamin D and Bone (1) | ECE2015

Secondary hyperparathyroidism in HIV patients and its relation to cardiovascular risk factors

Blanco Manuel Cayon , Garcia-Figueras Mateos Carolina , Pardo Rosa Marquez , Herrera Patricia Bancalero , Pernia Alberto Terron , Cortes Salvador Perez

Rationale: Low level of vitamin D can results in secondary hyperparathyroidism (SH) that has been linked to increased cardiovascular risk in general population. However, the spectrum of cardiovascular risk associated with SH in HIV-infected adults remains uncertain. Our main aim was to determine its potential association with different markers of cardiovascular risk in HIV-infected adults.Methods: Cross-sectional study. Clinical data related to obesity, ...
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ea0037gp.11.05 | Calcium, Vitamin D and Bone (1) | ECE2015

Determination of reference values for serum total 1,25-dihydroxyvitamin D3 using an extensively validated 2D ID-UPLC–MS/MS method

Dirks Niek , Martens Frans , Vanderschueren Dirk , Billen Jaak , Ackermans Mariette , Endert Erik , Blankenstein Marinus , Heijboer Annemieke

1,25-dihydroxyvitamin D3, the hormonally active metabolite of vitamin D3, tightly controls calcium blood levels. An increase of 1,25-dihydroxyvitamin D3 leads to an increase in calcium concentration with calcium originating from various resources, including bone tissue. To assess a patient’s vitamin D status the precursor metabolite 25-hydroxyvitamin D3 is determined. However, measurement of 1,25-dihydroxyvitamin D is required w...
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ea0037gp.11.06 | Calcium, Vitamin D and Bone (1) | ECE2015

Relationship between serum 25-hydroxivitamin D3 and adipose tissue vitamin D receptor gene expression with obesity and type 2 diabetes

Munoz-Garach Araceli , Clemente-Postigo Mercedes , Fernandez-Garcia Diego , Cardona-Diaz Fernando , Macias-Gonzalez Manuel , Tinahones-Madueno Francisco

Introduction: 25-hydroxyvitamin D (25(OH)D3) deficiency has been associated with diabetes and obesity. However, the mechanisms underlying these relationships are not completely understood. Vitamin D receptor (VDR) is expressed in adipose tissue; it has been reported a higher expression in obese patients than in lean subjects, suggesting a differential vitamin D dynamics in adipose tissue according to the obesity degree. In addition, 1, 25-dihydroxyvitamin D3 (1,25(OH)2D3) is a...
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ea0037gp.11.07 | Calcium, Vitamin D and Bone (1) | ECE2015

Tainted vitamin D responses under methyl donor deficiency of the pre-osteoblast cells are caused by a decreased VDR expression and a disruption of PGC-1a: VDR co-regulators complex

Feigerlova Eva , Ewu Essi , Battaglia Shyuefang , Leininger Brigitte , Weryha Georges , Gueant Jean-Louis

Folate and cobalamin are methyl donors (MD) needed for synthesis of methionine, precursor of S-adenosylmethionine (SAM), the substrate of methylation in epigenetic, and epigenomic pathways. The MD deficiency (MDD) leads to a decrease in SAM/SAH ratio and hyperhomocysteinemia, which has been related to osteoporosis in humans and disruption of development of epiphyseal cartilage in rat. However, the underlying molecular mechanisms remain elusive.M...
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ea0037gp.11.08 | Calcium, Vitamin D and Bone (1) | ECE2015

Associations of visceral and hepatic fat with serum 25-hydroxyvitamin D concentrations

de Jongh Renate , de Mutsert Renee , Lips Paul , Rosendaal Frits , den Heijer Martin

Introduction: Obesity is associated with lower serum 25-hydroxyvitamin D (25(OH)D) concentrations. A major explanatory hypothesis is that vitamin D is sequestered by adipose tissue. Another hypothesis is a decreased hepatic activation by 25-hydroxylase in obese individuals. Because adipose tissue has different characteristics and functions in different parts of the body an important question is whether serum 25(OH)D is more strongly related to visceral (VAT), hepatic, or total...
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ea0037gp.11.09 | Calcium, Vitamin D and Bone (1) | ECE2015

Physical performance in women with vitamin D deficiency

Capatina Cristina , Carsote Mara , Berteanu Mihai , Poiana Catalina

Introduction: VD deficiency is associated with the atrophy of muscle fibres (predominantly type II). This leads to decreased muscle force and general physical performance.Objective: To analyse the relationship between the serum concentration of 25-hydroxy vitamin D (25OHD), balance and physical performance in women with VD deficiency and the effect of VD supplementation or treatment with a VD analog.Materials and methods: We analys...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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