ECE2015 Eposter Presentations Diabetes (complications & therapy) (143 abstracts)
Can the onset of type 2 diabetes be delayed by a group-based lifestyle intervention in women with prediabetes following gestational diabetes mellitus? Findings from a randomised control mixed methods trial
Angela O’Dea 1 , Marie Tierney 1 , Brian McGuire 1 , John Newell 1 , Irene Gibson 2 , Liam Glynn 1 , Eoin Noctor 1 , Susan Connolly 3 & Fidelma Dunne 1
1National University of Ireland, Galway, Ireland; 2Croí West of Ireland Cardiac Foundation, Galway, Ireland; 3Imperial College London, International Centre for Circulatory Health, London, UK.
Aim: The aim of this paper is to report on the outcomes of a randomized controlled trial designed to evaluate the effectiveness of a group-based lifestyle intervention programme for reducing the risk factors associated with diabetes in women with pre diabetes following gestational diabetes. We expected that the group based intervention through its educational and supportive approach would enable improvements in psychosocial health, health behaviours, anthropometry, and glucose function.
Design and methods: A two groups, mixed methods randomized controlled trial in which 50 women with a history of gestational diabetes mellitus (GDM) and abnormal glucose tolerance postpartum were randomly assigned to MyAction (n=24) or wait control (n=26). The primary outcome variable was the change in fasting plasma glucose (FPG) from study entry to 1-year follow-up. Secondary outcomes were: glucose tolerance (2 h), insulin resistance, lipid profile, weight, shape, diet, and exercise levels. The role of mood, cognition and wellbeing were also explored. Post intervention qualitative interviews with participants are also reported.
Results: At 1-year follow-up, the intervention group showed significant improvements over the wait control group on stress, diet self-efficacy, and quality of life. There was no evidence of an effect of the intervention on measures of biochemistry or anthropometry the effect on one health behaviour – diet adherence, was close to significance. For many participants improvements made during the intervention were not sustained in the post intervention period.
Conclusions: Optimal approaches for preventative measures must tackle the barriers to participation faced by this population, home-based interventions should be investigated. Strategies for promoting long-term health self-management need to be developed and tested. The role of psychosocial factors in facilitating health related behaviour change should be explored further.
Disclosure: This work was funded by the Health Research Board of Ireland, Interdisciplinary Capacity Enhancement Grant number ICE/2011/3.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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