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Endocrine Abstracts (2015) 37 EP860 | DOI: 10.1530/endoabs.37.EP860

1Endocrinology Department, Puerto Real University Hospital, Puerto Real, Cádiz, Spain; 2Internal Medicine Department, Puerto Real University Hospital, Puerto Real, Cádiz, Spain; 3Surgery Department, Puerto Real University Hospital, Puerto Real, Cádiz, Spain; 4Clinical Information Department, Puerto Real University Hospital, Puerto Real, Cádiz, Spain.


Background: Recent studies have shown that the incidence of differentiated thyroid cancer (DTC) is increasing.

Objective: Evaluate the incidence of DCT in a center of the south of Spain for the last 15 years and analyse the clinical and morphological factors related to DTC.

Methods: We reviewed the series of patients undergoing thyroid surgery at our hospital over a 15-year period and identified patients with DTC. Patients were divided in three periods: 2000–2004, 2005–2009 and 2010–2014 and incidence rates were calculated. The variables gathered were age, sex, date of diagnosis, clinical presentation, hormonal status and cytology, size, morphology and extension of the tumour.

Results: patients with DTC were diagnosed. A significant increase in the number of DTC was shown in the period ranging from 2010 to 2014 (105 cases; 17.1% of the surgeries) compared to 71 cases between 2005 and 2009 (14.2% of interventions) and 48 cases between 2000 and 2004 (9.8% of interventions) (P<0.001). Incidence rates also increased from 3.7 (2000–2004 period) to 4.8 (2005–2009 period) and 6.8/1 00 000 habitants (2010–2014 period) (P<0.001) and this trend was found in both genders. The incidence was 3.1 times higher in women than in men and the most frequent morphology was papillary carcinoma (90.6%). No differences were found in the prevalence of microcarcinoma, extrathyroidal extension, lymph node involvement or distance metastases in the analysed periods.

Conclusions: We report a similar rise in the incidence of DTC in the south of Spain to the overall reported in the international literature.

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