Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2015) 37 GP16.06 | DOI: 10.1530/endoabs.37.GP.16.06

Department of Endocrinology, Sousse, Tunisia.


Background: Although the issue of cardiovascular complications in type 2 diabetic patients is widely discussed and recommendations for such screening are known, it is less common to do so for type 1 diabetes mellitus (T1DM). Unfortunately, the mortality rate due to vascular complications is higher among type 1 diabetic patients than in the general population.

Patients and methods: Seventy-six patients with T1DM history over 20 years were included in our study. We analysed the occurrence of cardiovascular complications and their risk factors: BMI, HbA1c, lipid profile, hypertension, smoking, alcohol consumption and family history of cardiovascular diseases and diabetes

Results: A total of 76 patients were enrolled: 43 men and 33 women, the mean age and the mean diabetes duration was 39.9 years ±9.5 (24–61 years) and 28.18±5.9 years respectively. The HbA1c was 10.26±1.76%. Smoking was present in 23.7% of our patients;hypertension was associated in 25.3±4,3% and dyslipidaemia in 11.3±3.18% The frequency of chronic diabetic complications was as follows: diabetic retinopathy =75%,peripheral polyneuropathy=55.3% and nephropathy=28.9%. 9/76 patients had cardiovascular complications: among this group eight patients were smoker, seven had a family history of diabetes mellitus and six without nephropathy. Proven stroke was diagnosed in six patients with over 20 years of T1DM history, coronary disease and peripheral arteriopathy were present in three and two patients respectively.

Conclusion: Beyond 20 years of diabetes history, cardiovascular complications dominate the prognosis.

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