Endocrine Abstracts (2015) 38 P69 | DOI: 10.1530/endoabs.38.P69

Endometrial hyperplasia in transmen: to scan or not to scan?

Leighton Seal1,2, Iffy Middleton2 & James Barrett2


1St George’s University Hospital NHS Foundation Trust, London, UK; 2West London Mental Health NHS Trust, London, UK.


Endometrial hyperplasia has been reported in up to 15% of transmen. For this reason the current clinical practice suggest that the uterus should be scanned every 2 years.

This is the single centre retrospective audit study at the largest UK Gender Identity Clinic to examine the incidence of endometrial hyperplasia in transmen.

Between 2006 and 2012. 200 patients having been maintained on testosterone therapy for 2 years, of those 108 transmen were requested to undergo ultrasound scanning and 42 scans were available to us at the time of study.

None of them had had endometrial thickness of >10 mm.

Abnormalities were seen in eight patients the largest thickness being 8 mm but this was known prior to the patient being started on testosterone therapy. Other issues that were apparent were fibroids PCOS and endometriosis.

This raises the question that the current recommendations biannual endometrial scanning should be maintained however further evidence is required before it is removed from the current type of practice guidelines.

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