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Volume 38
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SFEBES2015
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Society for Endocrinology BES 2015
Edinburgh,
UK
02 Nov 2015 - 04 Nov 2015
All volumes
0104 SFEIES24
0103 BSPED2024
0102 EYES2024
0101 ETA2024
0100 SFEEU2024
0099 ECE2024
0098 NANETS2023
0097 BES2023
0096 UKINETS2023
0095 BSPED2023
0094 SFEBES2023
0093 EYES2023
0092 ETA2023
0091 SFEEU2023
0090 ECE2023
0089 NANETS2022
0088 BES2022
0087 UKINETS2022
0086 SFEBES2022
0085 BSPED2022
0084 ETA2022
0083 EYES2022
0082 SFEEU2022
0081 ECE2022
0080 UKINETS2021
0079 BES2021
0078 BSPED2021
0077 SFEBES2021
0076 CHD2021
0075 EYES2021
0074 SFENCC2021
0073 ECE2021
0072 UKINETS2020
0071 BES2020
0070 ECE2020
0069 SFENCC2020
0068 UKINETS2019
0067 EYES2019
0066 BSPED2019
0065 SFEBES2019
0064 BES2019
0063 ECE2019
0062 EU2019
0061 OU2019
0060 UKINETS2018
0059 SFEBES2018
0058 BSPED2018
0057 BES2018
0056 ECE2018
0055 SFEEU2018
0054 NuclearReceptors2018
0053 OU2018
0052 UKINETS2017
0051 BSPED2017
0050 SFEBES2017
0049 ECE2017
0048 SFEEU2017
0047 Theranostics2016
0046 UKINETS2016
0045 BSPED2016
0044 SFEBES2016
0043 WCTD2016
0042 Androgens2016
0041 ECE2016
0040 ESEBEC2016
0039 BSPED2015
0038 SFEBES2015
0037 ECE2015
0036 BSPED2014
0035 ECE2014
0034 SFEBES2014
0033 BSPED2013
0032 ECE2013
0031 SFEBES2013
0030 BSPED2012
0029 ICEECE2012
0028 SFEBES2012
0027 BSPED2011
0026 ECE2011
0025 SFEBES2011
0024 BSPED2010
0023 BSPED2009
0022 ECE2010
0021 SFEBES2009
0020 ECE2009
0019 SFEBES2009
0018 MES2008
0017 BSPED2008
0016 ECE2008
0015 SFEBES2008
0014 ECE2007
0013 SFEBES2007
0012 SFE2006
0011 ECE2006
0010 SFE2005
0009 BES2005
0008 SFE2004
0007 BES2004
0006 SFE2003
0005 BES2003
0004 SFE2002
0003 BES2002
0002 SFE2001
2-4 November 2015, Edinburgh, UK
Further information
Summary
Abstract Book
Programme
Volume Editors
eposters
Abstracts
Contents
Plenary Lecturers’ Biographical Notes
Society for Endocrinology Starling Medal Lecture
Hyperactive PI-3-kinase signalling without hormone excess: between cancer and endocrinology
ea0038pl1
Society for Endocrinology Starling Medal Lecture
ea0038pl1biog
Society for Endocrinology Medal Lecture
Kisspeptin - a vital trigger of puberty with therapeutic potential
ea0038pl2
Society for Endocrinology Medal Lecture
ea0038pl2biog
Society for Endocrinology Transatlantic Medal Lecture
An integrated view of nuclear receptor/chromatin interactions: From genome wide to real time molecular dynamics
ea0038pl3
Society for Endocrinology Transatlantic Medal Lecture
ea0038pl3biog
Society for Endocrinology Dale Medal Lecture
Calcium regulation: from rhinos to molecules
ea0038pl4
Society for Endocrinology Dale Medal Lecture
ea0038pl4biog
British Thyroid Association Pitt-Rivers Lecture
Abstract unavailable
ea0038pl5
British Thyroid Association Pitt-Rivers Lecture
ea0038pl5biog
Clinical Endocrinology Trust Lecture
Mining the steroid metabolome in adrenal hormone excess
ea0038pl6
Clinical Endocrinology Trust Lecture
ea0038pl6biog
Clinical Endocrinology Trust Visiting Professor Lecture
Confronting the last frontiers of endocrine hypertension
ea0038pl7
Clinical Endocrinology Trust Visiting Professor Lecture
ea0038pl7biog
Society for Endocrinology European Medal Lecture
Repositioning mineralocorticoid receptor antagonists in renal diseases: pathophysiological basis and therapeutic implications
ea0038pl8
Society for Endocrinology European Medal Lecture
ea0038pl8biog
Society for Endocrinology International Medal Lecture
Controlling the freedom of steroids in health and disease
ea0038pl9
Society for Endocrinology International Medal Lecture
ea0038pl9biog
Society for Endocrinology Journal Awards
Society for Endocrinology Journal Award ‐
Journal of Endocrinology
Potential biomarker of metformin action
ea0038ja1
Society for Endocrinology Journal Award ‐
Journal of Molecular Endocrinology
1,25-vitamin D3 promotes cardiac differentiation through modulation of the WNT signaling pathway
ea0038ja2
Society for Endocrinology Journal Award ‐
Endocrine-Related Cancer
Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad
ea0038ja3
Society for Endocrinology Journal Award ‐
Clinical Endocrinology
Drugs that interact with levothyroxine: an observational study from the Thyroid Epidemiology, Audit and Research Study (TEARS)
ea0038ja4
Society for Endocrinology Journal Award ‐
Endocrine Connections
Role of endogenous ACTH on circadian aldosterone rhythm in patients with primary aldosteronism
ea0038ja5
Symposia
Endocrinology meets the environment
Later life consequences of maternal vitamin D deficiency - MAVIDOS study
ea0038s1.1
Iodine deficiency
ea0038s1.2
Environmental influences on autoimmunity
ea0038s1.3
Zoning in on adrenal tumours
Somatic mutations and adrenal remodelling in hyperaldosteronism
ea0038s2.1
Advances in genetic causes of adrenal Cushing's
ea0038s2.2
The new genetics of phaeochromocytoma
ea0038s2.3
Fanning the flames of mitochondrial function
Novel regulation of fat metabolism in cancer
ea0038s3.1
Abstract unavailable
ea0038s3.2
Mitochondrial disease: problems and solutions
ea0038s3.3
It's all in the timing: rhythms underlying endocrine systems
Sleep: what endocrinologists should know about the body clock
ea0038s4.1
Rhythms of adrenal glucocorticoid secretion
ea0038s4.2
Dynamics in hypothalamic-pituitary function over multiple time-scales
ea0038s4.3
Premature ovarian insufficiency
Abstract unavailable
ea0038s5.1
Neurological and psychological effects of premature ovarian insufficiency
ea0038s5.2
Abstract unavailable
ea0038s5.3
Clinical implications of thyroid genomics (Supported by
Journal of Molecular Endocrinology
)
Thyroid genomics: relevance to thyroid hormone therapy
ea0038s6.1
Abstract unavailable
ea0038s6.2
TCGA genomic characterization of papillary thyroid carcinoma
ea0038s6.3
The rise and rise of the FGFs in endocrinology
Abstract unavailable
ea0038s7.1
FGF21: starvation hormone to a clinical drug?
ea0038s7.2
The increasing understanding of FGF23 in pathogenesis and treatment of diverse endocrine disease
ea0038s7.3
Fine-tuning of metabolic state for optimal pregnancy outcome
Revolutionising type 1 diabetes metabolic control in pregnancy
ea0038s8.1
Pregnancy and obesity
ea0038s8.2
Autoimmune thyroid disease before and during pregnancy
ea0038s8.3
The endocrinology of the thin (Supported by
Endocrine Connections
)
Endocrine dysfunction in anorexia nervosa
ea0038s9.1
Abstract unavailable
ea0038s9.2
Abstract unavailable
ea0038s9.3
Blood and guts: how the intestine transduces nutritional cues to endocrine signals (Supported by
Journal of Endocrinology
)
Abstract unavailable
ea0038s10.1
The glucoregulatory role of small intestinal nutrient- and pharmacological-sensing
ea0038s10.2
Short chain fatty acids in the regulation of energy homeostasis
ea0038s10.3
Epigenetics in endocrine-related cancers (Supported by
Endocrine-Related Cancer
)
Oestrogen receptors and epigenetics in breast cancer aetiology and outcome
ea0038s11.1
Epigenetic regulation of androgen receptor function in prostate cancer
ea0038s11.2
Epigenetic signalling and acquired drug resistance in ovarian cancer
ea0038s11.3
Corticosteroids - getting to the heart of the matter (Supported by
Journal of Molecular Endocrinology
)
Abstract unavailable
ea0038s12.1
Selective targeting of the mineralocorticoid receptor in cardiovascular disease
ea0038s12.2
Mineralocorticoid receptor antagonists: lessons from clinical trials
ea0038s12.3
Clinical Management Workshops
Workshop 1: How do I do it? (Supported by
Clinical Endocrinology
and
Endocrinology, Diabetes & Metabolism Case Reports
)
How do I report and interpret a dual-energy X-ray absorptiometry scan?
ea0038cmw1.1
Abstract unavailable
ea0038cmw1.2
Abstract unavailable
ea0038cmw1.3
How do I manage adrenal suppression?
ea0038cmw1.4
How do I prevent thyroid eye disease after radioiodine?
ea0038cmw1.5
How do I manage suspected non compliance for thyroxine replacement?
ea0038cmw1.6
Workshop 2: Management of pituitary disease: beyond the adenoma
Abstract unavailable
ea0038cmw2.1
Abstract unavailable
ea0038cmw2.2
Abstract unavailable
ea0038cmw2.3
Workshop 3: Biological therapies - cause and cure of endocrine diseases
The thyroid and rituximab
ea0038cmw3.1
Endocrine sequelae of biological therapies (Campath, other MABs, etc.)
ea0038cmw3.2
Abstract unavailable
ea0038cmw3.3
Workshop 4: How do I do it? (II) (Supported by
Clinical Endocrinology
and
Endocrinology, Diabetes & Metabolism Case Reports
)
Abstract unavailable
ea0038cmw4.1
Abstract unavailable
ea0038cmw4.2
How far do I investigate chronic fatigue?
ea0038cmw4.3
How do I manage hirsutism?
ea0038cmw4.4
Managing hormone replacement therapy in the learning disabled young adult: a personal practice
ea0038cmw4.5
How do I manage men who have used anabolic steroids?
ea0038cmw4.6
Applied Physiology Workshop
Evolving model systems for complex tissues
Modelling human diseases with stem cell derived hypothalamic neurones
ea0038apw1.1
Abstract unavailable
ea0038apw1.2
Cell replacement and regeneration of [beta] cells as novel therapy for diabetes
ea0038apw1.3
Early Career Prize Lectures
(1)
The physiology and pharmacology of the fasting-induced hormone, FGF21
ea0038ecp1.1
Kisspeptin- A 'key regulator' of reproductive physiology, integrating limbic circuits with the regulation of reproductive hormones
ea0038ecp1.2
Meet the Expert Sessions
(1)
Cutting edge imaging of whole endocrine organs
ea0038mte1
Abstract unavailable
ea0038mte2
Optimising fertility in teenage cancer survivors
ea0038mte3
Investigation and management of TSHoma
ea0038mte4
Abstract unavailable
ea0038mte5
Frontiers in the management of hypoparathyroidism
ea0038mte6
Designer receptors exclusively activated by designer drugs (DREADD) - novel pharmacological handles on the endocrine system
ea0038mte7
Meet the Expert 8: updated thyroid cancer guidelines
ea0038mte8
Abstract unavailable
ea0038mte9
Diagnosis and management of SIADH meet the Expert 10
ea0038mte10
Skills
Skills 1: Working with the media
Why should we engage with the media?
ea0038sk1.1
Abstract unavailable
ea0038sk1.2
Abstract unavailable
ea0038sk1.3
Abstract unavailable
ea0038sk1.4
Skills 2: Early Career Symposium: Effective communication: get involved, get engaged!
Engaging with the public: conveying the wonders of science
ea0038sk2.1
The battles of writing a lay summary
ea0038sk2.2
Making science cool for kids
ea0038sk2.3
Making your impact statement: pack a punch
ea0038sk2.4
Making social media work for promoting and recruiting to research studies
ea0038sk2.5
Abstract unavailable
ea0038sk2.6
Futures
Futures 1: Branching out with endocrinology
Abstract unavailable
ea0038fut1.1
Abstract unavailable
ea0038fut1.2
The secret life of a core facilities manager
ea0038fut1.3
Futures 2: Overcoming the consultancy hurdle
Abstract unavailable
ea0038fut2.1
Abstract unavailable
ea0038fut2.2
Research pathways in endocrinology: a UK and global perspective
ea0038fut2.3
Futures 3: Why endocrinology and diabetes?
Abstract unavailable
ea0038fut3.1
Let me tell you the way it is: from a trainee's perspective
ea0038fut3.2
Endocrinology club in your medical school: from concept to reality, led by Cambridge example
ea0038fut3.3
Abstract unavailable
ea0038fut3.4
Debate
(1)
This house believe that patients with hypothyroidism should be offered combination treatment with T
3
and thyroxine if they do not respond to levothyroxine
ea0038d1.1
Abstract unavailable
ea0038d1.2
Nurse Session
Nurse Session 1: Multiple Endocrine Neoplasia
Overview of multiple endocrine neoplasia
ea0038n1.1
Genetics and multiple endocrine neoplasia
ea0038n1.2
Psychological support of the MEN patient
ea0038n1.3
Nurse Session 2: Nurse-led clinics
Abstract unavailable
ea0038n2.1
Abstract unavailable
ea0038n2.2
Medicolegal aspects of nurse-led clinics
ea0038n2.3
Senior Endocrinologists’ Session
(1)
The new tachykinin, endokinin: its role in emesis, sialorrhea and smoking in pregnancy
ea0038se1.1
Abstract unavailable
ea0038se1.2
Steroid mass spectrometry: a 50 year history
ea0038se1.3
A crackpot ejection theory about China's unique natural glass
ea0038se1.4
Understanding the biochemistry underpinning hypoglycaemia of the insulin autoimmune syndrome (IAS) is paramount for diagnosis and management
ea0038se1.5
Abstract unavailable
ea0038se1.6
Oral Communications
Early Career Oral Communications
A novel pharmacological approach to target LH and testosterone hypersecretion in women with polycystic ovary syndrome: a randomised, double-blind, placebo-controlled multi-centre randomised clinical trial of the neurokinin B receptor antagonist AZD4901
ea0038oc1.1
Mutations in IGSF10 cause self-limited delayed puberty, via disturbance of GnRH neuronal migration
ea0038oc1.2
RNA-sequencing of mouse adrenals reveals the pathways perturbed by loss of nicotinamide nucleotide transhydrogenase
ea0038oc1.3
Adipose tissue-specific androgen generation fuels an adverse metabolic phenotype in patients with polycystic ovary syndrome
ea0038oc1.4
Interaction of the MR and GR in the nucleus and at DNA
ea0038oc1.5
Urine steroid metabolomics as a diagnostic tool in primary aldosteronism
ea0038oc1.6
Translational pathophysiology and therapeutics
Dual 5-[alpha] reductase inhibition promotes hepatic lipid accumulation in man as a result of changes to lipid metabolism in adipose tissue and the liver
ea0038oc2.1
Adrenal vein catecholamine levels and ratios: reference intervals derived from patients with primary aldosteronism
ea0038oc2.2
Further advances in diagnosis of adrenal cancer: a high-throughput urinary steroid profiling method using liquid chromatography tandem mass spectrometry (LC-MS/MS)
ea0038oc2.3
Development of a long-acting growth hormone antagonist for the treatment of acromegaly
ea0038oc2.4
Age at first major osteoporotic fracture in Danes aged 50 and over: influence of diabetes on mean age at fracture and 1 year mortality
ea0038oc2.5
Treatment with the epigenetic modifying compound JQ1+ can significantly reduce the proliferation of pancreatic neuroendocrine tumours in a mouse model of multiple endocrine neoplasia type 1
ea0038oc2.6
Steroids and adrenal
Molecular diagnosis of patients with adrenal insufficiency using a targeted custom Haloplex next-generation sequencing panel
ea0038oc3.1
Glucocorticoids stabilise the microtubule network to inhibit cell migration
ea0038oc3.2
11[beta]-HSD1-mediated decrease in COX2 expression is abrogated by hypoxia in human dermal fibroblasts
ea0038oc3.3
Urine steroid metabolomics as a novel diagnostic tool for early detection of recurrence in adrenocortical carcinoma
ea0038oc3.4
Glucocorticoid pattern-dependent gene regulation in the rat hippocampus
ea0038oc3.5
Female 5[beta]-reductase knockout mice are protected from diet induced obesity, insulin resistance, and glucose intolerance
ea0038oc3.6
Diabetes and cardiometabolic complications
Acute intense exercise restores defective counter-regulation in type 1 diabetes through a process of dis-habituation
ea0038oc4.1
Thermal imaging as a novel non-invasive method to measure human brown adipose tissue activity in humans
ea0038oc4.2
5[alpha]-tetrahydrocorticosterone exhibits topical anti-inflammatory action with limited adverse effects on angiogenesis
ea0038oc4.3
Hyperinsulinaemia due to inhibition of 5[alpha]-reductases is ameliorated by liver-selective glucocorticoid receptor antagonism in diet-induced obesity
ea0038oc4.4
Glucagon increases energy expenditure independently of brown adipose tissue activation in humans
ea0038oc4.5
Cardiac fibrosis and the balance between glucocorticoid and mineralocorticoid receptors signalling
ea0038oc4.6
Thyroid and parathyroid
Functional consequences of germline mutations in a novel non-RET medullary thyroid cancer susceptibility gene
ea0038oc5.1
A novel, missense, mutation (P81R) in the TRH receptor gene in congenital central hypothyroidism
ea0038oc5.2
Use of 11C-methionine PET to localise parathyroid adenoma/hyperplasia: a single centre experience
ea0038oc5.3
A novel modulator of cellular invasion and metastasis in endocrine cancer
ea0038oc5.4
Investigating the genetic architecture of gland-in-situ congenital hypothyroidism by comprehensive screening of eight known causative genes
ea0038oc5.5
Safety review of liothyronine use: a 20 year observational follow up study
ea0038oc5.6
Advances in reproduction and signalling
Neurokinin B receptor antagonist limits kisspeptin-10 induced LH secretion in women
ea0038oc6.1
Kisspeptin-54 safely and effectively triggers oocyte maturation during IVF treatment in women at high risk of developing ovarian hyperstimulation syndrome (OHSS)
ea0038oc6.2
Mutations in HS6ST1 are causal in self-limited delayed puberty as well as idiopathic hypogonadotropic hypogonadism
ea0038oc6.3
Calcium-sensing receptor internalisation is impaired in cells expressing FHH3-associated AP2σ mutations
ea0038oc6.4
Pituitary tumor transforming gene binding factor (PBF): a novel modulator of iodide uptake and target for Src phosphorylation in breast cancer
ea0038oc6.5
Glucocorticoids induce rapid and persistent chromatin remodelling at a glucocorticoid receptor bound locus in macrophages
ea0038oc6.6
Featured Posters
(1)
Inhibition of NFAT signalling
in vivo
improves microvascular endothelial function in a mouse model of chronic diabetes
ea0038fp1
Corticosterone in human saliva is highly abundant and lacks a diurnal rhythm
ea0038fp2
Maternal genotype is an important determinant of the outcome of antenatal glucocorticoid treatment in GR+/+ and GR+/− foetal mice
ea0038fp3
GLP-1 reduces cerebrospinal fluid secretion and intracranial pressure: a novel treatment for idiopathic intracranial hypertension?
ea0038fp4
Generation of GnRH neurons from human embryonic stem cells and induced pluripotent stem cells of healthy individuals and patients with Kallmann's syndrome
ea0038fp5
The role of 11[beta]-hydroxysteroid dehydrogenase type 2 in the central regulation of blood pressure and salt appetite
ea0038fp6
Regulation of adipogenesis by wnt10b signalling in cultured human adipocytes taken from an obese patient with a WNT10B-C256Y mutation
ea0038fp7
Reduced circulating levels of kisspeptin, human chorionic gonadotropin, placental-like growth factor, soluble fms-like tyrosine kinase-1 and soluble endoglin but not prokineticin-1 are associated with miscarriage risk
ea0038fp8
How well can we measure oestradiol?
ea0038fp9
A dedicated Turners clinic improves adherence to UK recommended best practice and is well liked by patients
ea0038fp10
Potential molecular mechanism of AIP-mediated cellular invasion
ea0038fp11
Characterising the functional significance of the first reported mutations in the pituitary tumor-transforming gene binding factor
ea0038fp12
Poster Presentations
Bone
FHH3-associated AP2σ mutations impair MAPK signalling pathways
ea0038p1
Exploring the N-ethyl-N-nitrosourea mutagenesis DNA archive for mutations in nuclear factor I/X to derive mouse models for Marshall-Smith syndrome
ea0038p2
Reduction in daily hydrocortisone dose in adrenal insufficiency improves significantly bone mineral density - results from a 2-years prospective trial
ea0038p3
Mutations in G-protein subunit [alpha]
q
(GNAQ) are not a cause of familial hypocalciuric hypercalcaemia
ea0038p4
Soy protein with isoflavones reduce bone turnover markers in women during their early menopause - a randomised double blind parallel study
ea0038p5
Increased circulating sclerostin levels in type 2 diabetic rats are not associated with changes in bone sclerostin production
ea0038p6
Differential effects of parathyroid hormone on key regulators of osteoblast mineralisation
ea0038p7
Type 2 diabetes, bone mineral density and disc height
ea0038p8
The decreased plasma levels of sclerostin but not Dickkopf-1 are associated with increased risk of osteoporotic fracture and lower bone mineral density in Korean postmenopausal women
ea0038p9
A mutation in the calcium sensing receptor (previously known to cause neonatal severe hyperparathyroidism in the homozygote state) causing familial benign hypocalciuric hypercalcaemia in the heterozygote
ea0038p10
The effect of oestradiol circadian rhythm on the bone mineral density of adult males
ea0038p11
Familial hypocalciuric hypercalcaemia due to
AP2S1
mutation in a patient with failed parathyroidectomies: a case report
ea0038p12
Pre-operative localisation of parathyroid adenomas in patients with primary hyperparathyroidism: can a single modality of imaging be adequate?
ea0038p13
A rare presentation of primary hyperparathyroidism
ea0038p14
Lessons learnt after 'failed' parathyroidectomy
ea0038p15
Melorrheostosis: a rare cause of bone pain and limb deformity
ea0038p16
Denosumab improves bone density in a female patient with severe anorexia nervosa
ea0038p17
Improved glycaemia following parathyroidectomy for primary hyperparathyroidism
ea0038p18
Clinical biochemistry
A comparison of plasma copeptin and AVP responses during saline infusion studies
ea0038p19
Use of ADH antagonists results in lower hospital resource usage: a retrospective cohort study
ea0038p20
Genetic hypocalcaemia: a case of 22q deletion syndrome
ea0038p21
Effect of cortisol assay bias on the overnight dexamethasone suppression test: implications for the investigation of Cushing's syndrome
ea0038p22
Using SDHB immunostaining in characterising pheochromocytoma and paraganglioma
ea0038p23
Serum cortisol: what is your laboratory measuring?
ea0038p24
Vasopressin-2 receptor antagonists: potent but potentially dangerous drugs for the treatment of severe hyponatraemia secondary to syndrome of inappropriate antidiuretic hormone secretion
ea0038p25
Lactic dehydrogenase, a biochemical marker to predict foetal outcome in pregnancies complicated by intrauterine growth restriction
ea0038p26
Turn off the taps
ea0038p27
Where are the endocrinologists?
ea0038p28
The epidemiology of hyperprolactinaemia
ea0038p29
Audit of management of patients with hypomagnesaemia in district general hospital
ea0038p30
Single-centre audit of the diagnostic performance of plasma metanephrines with seated sampling for the diagnosis of phaeochromocytoma/paraganglioma
ea0038p31
An unusual presentation of osmotic demyelination syndrome
ea0038p32
Management of inpatient hypokalaemia: a District General Hospital (DGH) experience
ea0038p33
Alkaline phosphatase may predict tumour volume in patients with parathyroid adenoma
ea0038p34
Biochemical evaluation of adrenal incidentalomas referred to endocrine surgery in a large teaching hospital
ea0038p35
Inhibiting more than the proton pump
ea0038p36
Asymptomatic hypokalaemia in an identical twin
ea0038p37
Severe hyponatraemia in an inpatient setting - a role for the Endocrinologist?
ea0038p38
Are we doing to many short synecthan test
ea0038p39
A case of B cell lymphoma of brain presenting as syndrome of inappropriate antidiuretic hormone secretion
ea0038p40
Audit of the diagnosis and management of primary hyperparathyroidism
ea0038p41
Novel treatment of refractory hypercalcaemia: a serendipitous discovery
ea0038p42
Clinical practice/governance and case reports
What is the prevalence of severe post-operative hypocalcaemia in patients who have undergone parathyroid surgery or a total thyroidectomy at the RVI, Newcastle? Does vitamin D play a role?
ea0038p43
Urgent requirement for better patient selection for short Synacthen tests: results from a clinical audit
ea0038p44
Using Skype follow-up consultations for patients with thyroid disease
ea0038p45
Review in specialist Turner clinic improves management
ea0038p46
A rare incidental cause of Cushing's syndrome
ea0038p47
Partial response to sunitinib therapy in a metastatic dopamine-secreting paraganglioma
ea0038p48
Outcome of patients with adrenal incidentalomas: an analysis of 145 patients from a single centre
ea0038p49
Early post-operative aldosterone concentration can be used to assess outcome from adrenalectomy in aldosterone producing adenoma
ea0038p50
Saccular internal carotid artery aneurysm masquerading as pituitary macroadenoma
ea0038p51
Impact of a multidisciplinary diabetic foot clinic on patient outcomes
ea0038p52
Out-of-hours cover for diabetes and endocrinology: a single UK tertiary centre experience
ea0038p53
TB or not TB: that is the question
ea0038p54
A case of polyglandular autoimmune disease associated with common variable immunodeficiency
ea0038p55
Phaeochromocytoma in pregnancy: good luck and judgement lead to a successful outcome
ea0038p56
Audit on continuous subcutaneous insulin infusion (insulin pump) therapy
ea0038p57
Vitamin D deficiency in haemodialysis patients; treatment with colecalciferol
ea0038p58
DIPNECH: under-recognised and a diagnostic challenge
ea0038p59
Sodium-glucose co-transporter 2 inhibitor associated normoglycaemic ketoacidosis
ea0038p60
A novel management of Gitelman's syndrome
ea0038p61
Nothing to 'sea' here: turning a blind eye to hyponatraemia
ea0038p62
A case to remember
ea0038p63
Resistant hypocalcaemia secondary to denosumab: two case reports
ea0038p64
Multiple endocrine paraneoplastic syndromes in a patient with lung malignancy
ea0038p65
National Audit of Transition in Endocrinology: joint between Society for Endocrinology and the British Society of Paediatric Endocrinology and Diabetes
ea0038p66
IgG4-related hypophysitis: a novel candidate to the hypophysitis spectrum
ea0038p67
Management of thyroid disease in pregnancy: experience from an antenatal thyroid clinic
ea0038p68
Endometrial hyperplasia in transmen: to scan or not to scan?
ea0038p69
Steroid responsive hypoglycaemia in a patient with spindle cell sarcoma
ea0038p70
Does the usual time of rising influence the stimulated cortisol response?
ea0038p71
A woman with thyroid metastases 21 years after renal carcinoma excision, with biphasic thyroid dysfunction on sunitinib
ea0038p72
Immobilisation hypercalcaemia in two intensive care patients
ea0038p73
Audit on hyponatraemia in a West Kent Hospital experience
ea0038p74
Large benign nerve sheath tumour in the adrenal gland: an incidental finding
ea0038p75
Aromatase inhibitor: potential therapy for obesity related hypogonadotropic hypogonadism and gynaecomastia
ea0038p76
Phaeochromocytoma: experience from a single centre in South India
ea0038p77
Pituicytoma, not a 'meningioma': late recurrence in a rare pituitary tumour
ea0038p78
Somatotroph adenoma localised with composite 11C-methionine PET/MRI: a cost effective solution
ea0038p79
Vitamin D resistant idiopathic hypoparathyroidism
ea0038p80
Glycogenic hepatopathy: a tale infrequently told in the diabetes world
ea0038p81
Should all short Synacthen tests be agreed by an endocrine team?
ea0038p82
Artifactual hypoglycaemia: lesson from a patient with unreliable finger-prick glucose due to absent finger tips
ea0038p83
Decreased conscious level and a renal mass
ea0038p84
An index case of MEN1 identified with imaging of the right thigh
ea0038p85
Four years of tolvaptan: experience from two large teaching hospitals
ea0038p86
A single-centre experience of adrenal vein sampling in a District General Hospital serving a remote and rural population
ea0038p87
Haemofiltration as a treatment option in refractory life-threatening diabetic ketoacidosis
ea0038p88
Adrenal insufficiency caused by bilateral primary adrenal lymphoma
ea0038p89
Congenital adrenal hyperplasia: are we really lost in transition?
ea0038p90
Audit of Plenadren use in selected patients
ea0038p91
Clinical practice, governance, and case reports: hypovitaminosis D as a cause of severe hypocalcaemia in a Nigerian female
ea0038p92
Evaluation of use of combination dapagliflozin and GLP1 agonist treatment in type 2 diabetes
ea0038p93
Do guidelines improve the diagnosis and investigation of hyponatraemia?
ea0038p94
Diaphoresis: an unusual initial presenting complaint of Cushing's syndrome
ea0038p95
An unusual case of 'adrenal' Cushing's
ea0038p96
Accuracy of sample timing with short Synacthen tests at Royal Bournemouth Hospital
ea0038p97
Hyponatremia: an audit of the initial investigation and management
ea0038p98
A case of haemorrhagic adrenalitis due to streptococcus oralis
ea0038p99
Xerostomia: an unseen consequence of statin use
ea0038p100
A complex case of MEN1
ea0038p101
Hyperalphalipoproteinaemia in epileptic patient: cardiovascular protection from carbamaezipine use?
ea0038p102
Splenunculi masquerading as neuroendocrine tumours
ea0038p103
UK primary hyperparathyroidism clinical practice audit
ea0038p104
Pregnancy and lactation-associated osteoporosis: two case reports
ea0038p105
Pseudohypoparathyroidism: a case of delayed diagnosis
ea0038p106
Opiate induced multiple pituitary hormone deficits
ea0038p107
Separate, sequential, endocrine, and glycaemic effects of ipilimumab and pembrolizumab in metastatic melanoma
ea0038p108
Resistant hyperparathyroidism and hepatitis: is there a link?
ea0038p109
Hypogonadism in Noonan syndrome
ea0038p110
Hungry bones: a case of severe complications post parathyroidectomy
ea0038p111
Carbarmazepine and Cushing's: a cautionary tale of assay interference mimicking disease
ea0038p112
Foreign bariatric procedures: help or hindrance for the NHS?
ea0038p113
Variation in levels of macroprolactin in the investigation of secondary hypogonadism
ea0038p114
Audit of adult GH replacement therapy in Nottingham
ea0038p115
Erectile dysfunction, diabetes mellitus, and sun-tan: the hypogonadism story with a difference
ea0038p116
Cardiac manifestations of a phaeochromocytoma
ea0038p117
Management of patients with adrenal insufficiency attending Galway University Hospital compared with current best practice
ea0038p118
An audit in to the investigation of spontaneous hypoglycaemia: experience at a tertiary centre
ea0038p119
Cyclophosphamide induced seminiferous tubule damage causing raised FSH and LH, and high testosterone levels
ea0038p120
A case of morning headache: Doege-Potter syndrome
ea0038p121
The effects of maggot debridement therapy on length of hospital inpatient stay
ea0038p122
A case of adrenal haemorrhage in severe sepsis
ea0038p123
A case of Graves' disease occurring following cessation of the oral combined contraceptive pill
ea0038p124
Benign or malignant adreno-cortical tumour; the relevance of size and androgen secretory capacity
ea0038p125
Three cases highlighting the varied clinical presentations of adrenal haemorrhages
ea0038p126
Asymptomatic Paget's disease of the bone in a 62-year-old Nigerian man: 3 years post alendronate therapy
ea0038p127
Does thyroid armour cause autoimmune thyroid disease?
ea0038p128
Cytokines and growth factors
Expression of cytokines in placenta from pregnancies complicated by intrauterine growth restriction with abnormal umbilical artery Doppler indices
ea0038p129
Interleukin 27: a predictive marker for diabetic retinopathy progression
ea0038p130
Growth and development
Hormonal control of [beta]-cell proliferation in fetal ovine pancreatic islets
in vitro
ea0038p140
Inter-correlations between placental genes regulating foetal glucocorticoid exposure and IGF2 in maternal severe obesity: a mechanism for higher birthweight?
ea0038p141
Human foetal adrenal gland development and effects of maternal smoking
ea0038p142
Vitamin D promotes myogenic differentiation and induces an antifibrotic phenotype in primary cultures of skeletal muscle derived satellite cells and fibroblasts
ea0038p143
Hypothyroidism, altered leptin and c-reactive protein synthesis characterised pregnancy exposed to genistein
ea0038p144
Neoplasia, cancer and late effects
Nicotinamide nucleotide transhydrogenase (NNT) as a novel molecular target in adrenocortical carcinoma - impact of NNT knockdown on adrenocortical cell proliferation, redox balance and steroidogenesis
ea0038p145
The somatostatin analogue pasireotide decreased proliferation and increased apoptosis in pancreatic and pituitary neuroendocrine tumors in a MEN1 mouse model
ea0038p146
Steroid sulphatase and G-protein coupled oestrogen receptor in human colorectal cancer: correlation with late-stage disease and potential therapeutic targets
ea0038p147
PTTG is phosphorylated at residue T60 and regulates p53 stability, in conjunction with PBF, in head and neck cancer
ea0038p148
Distinct p53 response profiles in transgenic mouse models of thyroid-specific PBF and PTTG expression
ea0038p149
Follow up of differentiated thyroid cancer survivors during pregnancy: a retrospective analysis
ea0038p150
Pituitary-related outcomes of cranial radiotherapy (cXRT) in adults with gliomas
ea0038p151
Phenotypic heterogeneity associated with proglucagon-expressing tumours is due to differential processing and secretion of proglucagon-derived peptides
ea0038p152
Novel targeted treatment combinations for malignant neuroendocrine tumour olfactory neuroblastoma
ea0038p153
Adrenal pigmentation in PPNAD is a result of melanin deposition and associated with upregulation of the melanocortin 1 receptor
ea0038p154
Primary cilia: a new player in phaeochromocytoma pathogenesis?
ea0038p155
Adverse metabolic profile in long-term survivors of adult and childhood-onset brain tumours: the role of growth hormone deficiency
ea0038p156
Ultrasound-guided percutaneous ethanol ablation for selected patients with papillary thyroid microcarcinoma: a novel, effective and well tolerated alternative to neck surgery or observation
ea0038p157
Clot structure analysis in survivors of acute lymphoblastic leukaemia: the role of growth hormone deficiency
ea0038p158
Use of Sunitinib in refractory hypercalcaemia in pancreatic neuroendocrine tumours
ea0038p159
Chromogranin B: a possible prognostic biomarker for neuroendocrine tumours?
ea0038p160
Imaging and evaluating side effects of antiandrogen therapy
ea0038p161
Outcome of insulinomas diagnosed in a tertiary endocrine centre
ea0038p162
Metastatic paraganglioma with isolated 3-methoxytyramine rise in a patient with SDHC mutation
ea0038p163
Recurrent phaeochromocytomas in type2C variant of Von Hippel-Lindau syndrome
ea0038p164
Lutetium ablation therapy as treatment for recurrent metastatic bladder paraganglioma
ea0038p165
Somatostatin responsive ACTH and precursor excess in a midgut mesentery NET
ea0038p166
Primary adrenal lymphoma
ea0038p167
Metastatic bowel carcinoid associated bilateral carcinoid heart disease
ea0038p168
Familial insulinoma in the absence of MEN
ea0038p169
A young girl with bilateral adrenal tumours
ea0038p170
Acromegaly in association with a bronchial carcinoid tumour
ea0038p171
Challenges in the diagnosis and management of a case of glucagonoma first presenting as a localised genital rash
ea0038p172
A management dilemma - emergency treatment of primary hyperparathyroidism in suspected but unconfirmed multiple endocrine neoplasia type 1
ea0038p173
Promoter methylation signatures of BRCA2 and TP53 genes in the serum of some breast cancer patients attending radiotherapy clinic in Lagos, Nigeria
ea0038p174
Confusion in a patient with carcinoid syndrome
ea0038p175
Nursing practise
Utilisation of nurse led clinics in endocrinology practice
ea0038p176
How is the Society for Endocrinology Competency Framework for Adult Endocrine Nursing used in practice?
ea0038p177
Pre-pituitary surgery patient satisfaction audit 2015
ea0038p178
Development of IT based nurse led endocrine tracking system
ea0038p179
A care service model for cost effective and structured individualised treatment choice for GH replacement therapy
ea0038p180
Recurring abscesses at injection sites on the home injection programme
ea0038p181
Obesity, diabetes, metabolism and cardiovascular
Testing causality in the association of plasma cortisol with risk of coronary heart disease: a Mendelian randomisation study
ea0038p182
Gender-related differences in circulating microparticles characteristics: implications for cardiovascular risk?
ea0038p183
Longer duration of sitting down in pregnancy is associated with gestational diabetes, greater weight gain and depressive symptoms
ea0038p184
Transcriptome profiles of human pancreatic islets following transient ischemia identify inflammatory and cell death responses
ea0038p185
Studies of Nuf mice with an activating calcium-sensing receptor (CaSR) mutation demonstrate the CaSR to regulate pancreatic beta-cell mass and glucose homeostasis
ea0038p186
Role of oral cholecalciferol as adjuvant therapy in type 1 diabetes mellitus: randomised controlled trial
ea0038p187
Prevalence and determinants of metabolic syndrome among HIV infected patients receiving highly active antiretroviral therapy in Kano, northwestern Nigeria
ea0038p188
The effect of L-arginine on anorectic gut hormone release in humans
ea0038p189
Generation of a long acting GCSF for treatment of neutropenia and stem cell harvest
ea0038p190
Hypercortisolaemia increases femoral adipose tissue blood flow but not net fatty acid release
in vivo
ea0038p191
Central IL6 signalling and the development of impaired insulin secretion in type2 diabetes
ea0038p192
Women with idiopathic intracranial hypertension have a distinct andro-metabolic signature compared to polycystic ovary syndrome and simple obesity
ea0038p193
Differences between men and women in markers of dietary fatty acid oxidation
ea0038p194
Establishing human liver cell models to investigate the effects of exogenous metabolic substrates on fatty acid partitioning
ea0038p195
Evidence for 11[beta]-HSD1 regulation of brain energy metabolism following systemic inflammation
ea0038p196
Impact of number of transplanted human islet equivalents on successful return to normoglycaemia in an NSG diabetic mouse model
ea0038p197
Vascular dysfunction in horses with insulin resistance
ea0038p198
Evidence for improved mitochondrial efficiency in adipose tissue of T2DM women after malabsorptive but not restrictive bariatric surgery
ea0038p199
AMPK activators modulate pro-inflammatory responses in human adipocytes
ea0038p200
eNAMPT-monomer plays a critical role in pathophysiology of experimental diabetes and represents a novel target for treatment of type 2 diabetes
ea0038p201
Predictors of glycaemic response and impact on weight and BP of dapagliflozin therapy in type 2 diabetes
ea0038p202
Pre-operative assessment for Sleep apnoea in patients referred for bariatric surgery: the usefulness of various clinical screening tools
ea0038p203
Effect of vitamin D supplementation on cardiovascular risk factors and exercise performance in healthy subjects; a randomised placebo controlled pilot study
ea0038p204
Evaluation of adipocytokines and traditional cardiometabolic risk factors in young male cancer survivors: an age-matched control study
ea0038p205
Low vitamin B12 in pregnancy is associated with maternal obesity and gestational diabetes
ea0038p206
Adrenaline mediated metabolic and functional quiescence protects insulin producing cells from hypoxia
ea0038p207
Bile acids stimulate GLP-1 release predominantly by accessing basolateral GPBAR1 (TGR5)
ea0038p208
Vitamin B12 deficiency alters adipogenesis and associated microRNA's in human adipocytes
ea0038p209
Proteomic detection of extracellular matrix proteins in insulin-resistant skeletal muscle
ea0038p210
Longitudinal changes in adipose tissue gene expression profile are asociated with deteriorating glucose tolerance
ea0038p211
Distinguishing different subtypes of aldosterone-producing adenoma by histological, immunohistochemical and radiological features; a basis for individualised treatment strategies in primary aldosteronism?
ea0038p212
Adrenal insufficiency following bariatric surgery
ea0038p213
Discovery and localisation of the expression of calcitonin-type and CRH-type neuropeptide precursors in an echinoderm
ea0038p214
The role of vitamin B12 deficiency in molecular mechanism of metformin
ea0038p215
Enhanced orbitofrontal cortex activation following sympathetic neural stimulation in young women with polycystic ovary syndrome: an fMRI study
ea0038p216
Enhanced insulin secretion and insulin action in young lambs with intrauterine growth restriction
ea0038p217
Glucocorticoid excess increases hypothalamic AgRP and results in obesity and hyperinsulinaemia in mice
ea0038p218
Non-selective beta-adrenergic agonist infusion acutely stimulates the temperature of brown adipose tissue in adult males
ea0038p219
Endogenous ARX knockdown enhances beta-cell lineage specification and maturation during
ex vivo
transdifferentiation of human exocrine pancreatic tissue
ea0038p220
Altered adipocytes in an ovine model of polycystic ovary syndrome
ea0038p221
Transcriptional profiles explain insulin hypersecretion following chronic adrenergic stimulation in foetal sheep islets
ea0038p222
Measuring the contribution of de novo lipogenesis to fatty liver disease: a mouse and translational human study using high resolution mass spectrometry
ea0038p223
The hypoglycaemic and antioxidant properties of oleanolic acid ameliorate blood pressure and kidney function of experimental animals
ea0038p224
Dietary cocoa (Theobroma cacao) and turmeric (Curcuma longa) consumption: a comparison of metabolic effect in high-fat fed rats
ea0038p225
Glucose tolerance, insulin sensitivity and adiponectin level in niacin-treated obese rats
ea0038p226
Circadian rhythm of ambulatory blood pressure in rotating night shift nursing professionals and its relation with 6- sulfatoxy melatonin as neuroendocrine chronomolecule
ea0038p227
Characterising fat distribution and response to weight loss in idiopathic intracranial hypertension
ea0038p228
Anti-inflammatory effects of metformin and their relationship to the therapeutic action of the drug
ea0038p229
Maternal overnutrition programs hypothalamic neuropeptides and metabolic syndrome in offspring
ea0038p230
'Thin-fat' phenotype in early foetal life in GDM pregnancies - novel evidence from an Indian Cohort
ea0038p231
Functional significance of renal gene expression changes in a mouse model of ACTH-dependent Cushing's syndrome
ea0038p232
Brown adipose tissue plays a role in regulating fetal growth by undergoing a gestational-dependent phenotypic change
ea0038p233
Seasonal variation of HbA
1c
ea0038p234
Relationship between high-sensitivity C-reactive protein and anthropometric indices of obesity
ea0038p235
2[beta]-hydroxybetulinic acid 3[beta]-caprylate: an active principle from euryale ferox salisb. seeds with antidiabetic, antioxidant, pancreas & hepatoprotective potential in streptozotocin induced diabetic rats
ea0038p236
Clinical profile and outcome of patients with hyperglycaemic emergencies presenting at a rural hospital in southern Nigeria
ea0038p237
Diabetic neuropathy: an evaluation using the ntss-6 questionnaire and biothesiometry in type 2 DM patients
ea0038p238
Hypothalamic glucocorticoid levels increase in an in vivo model of glucocorticoid-induced obesity and hyperinsulinaemia
ea0038p239
Effects of androgen on the adipokinome and metabolic genes in white and brown adipose tissue
ea0038p240
From the bronze age to the iron age
ea0038p241
Characterisation of the astrocytic response to acute and recurrent hypoglycaemia
ea0038p242
Markers of adipose tissue hypoxia are elevated in subcutaneous adipose tissue of morbidly obese patients with hypoventilation syndrome and obstructive sleep apnoea syndrome but not in the moderately obese
ea0038p243
Prevalence of diabetes mellitus among HIV patients in Kano, northwestern Nigeria
ea0038p244
Obstructive sleep apnoea and bariatric surgery: the need for more universal screening and post-operative follow up
ea0038p245
The effect of soy protein with and without isoflavones in men with type 2 diabetes mellitus and subclinical hypogonadism: a randomised double-blind parallel study
ea0038p246
Is polycythaemia a marker of an increased cardiovascular risk in transmen?
ea0038p247
Cost of illness among patients with diabetic foot ulcer in secondary and tertiary health facilities in Kano, northwestern Nigeria
ea0038p248
Impact of DAFNE and subsequent CSII therapy on glycaemic control in type 1 diabetes mellitus
ea0038p249
Lifelong exposure to sewage sludge chemicals causes proteome-wide and sex-specific disturbances in the liver
ea0038p250
GLP1 agonist based therapy has modest effect on weight and glycaemic control among UAE patients with diabetes: analysis of data on 3725 patients
ea0038p260
Extracts of
Hymenocardia acida
ameliorate insulin resistance in skeletal muscle cells
ea0038p261
A study of metabolic syndrome among HAART naive HIV patients in Kano, northwestern Nigeria
ea0038p262
Anthropometric indices: optimal cut-off values for abdominal obesity in adult Nigerians
ea0038p263
Influence of gender on the distribution of type 2 diabetic complications at the Obafemi Awolowo Teaching Hospital, Ile-Ife, Nigeria
ea0038p264
A study of the influence of West African ethnicity and gender on [beta]-cell function and insulin sensitivity in essential hypertensives treated with hydrochlorothiazide and hydrochlorothiazide-lisinopril combination
ea0038p265
Comparison of surrogate measures of percentage body fat with bioelectric impedance in Nigerians
ea0038p266
Evidence of foetal growth restriction in South-Asian foetuses of GDM mothers?
ea0038p267
Prediabetes incidence and risk of developing cardiovascular disease in women with polycystic ovary syndrome
ea0038p268
Improving glycaemic control in T1DM: the Fife Insulin and Food Education for Diabetes (FIFE Diabetes) structured education programme
ea0038p269
Intra-Individual correlation between flow mediated dilation and reactive hyperaemia peripheral arterial tonometry in PCOS
ea0038p270
Evaluation of hypoglycaemia unawareness in individuals with type 1 diabetes mellitus using continuous glucose monitoring in a tertiary care centre
ea0038p271
Postnatal screening in patients with gestational diabetes
ea0038p272
Prevalence of vitamin D deficiency and its association with diabetes in a South-Asian population
ea0038p273
What the mouth has to say about diabetes in a Nigerian Tertiary Hospital
ea0038p274
Anthropometric indexes correlate of body fat percentage among Nigerians
ea0038p275
Lipid profile in apparently healthy Nigerian adults
ea0038p276
Overweight and obesity in a rural Nigerian adult population
ea0038p277
Comparison of glycaemic control in patients with type-1 diabetes mellitus on CSII therapy with different basal rates
ea0038p278
Effects of gypenoside on pancreatic beta cell function and insulin secretion
ea0038p279
GPR142 plays a critical role in Tryptophan-induced insulin and incretin secretion in mice
ea0038p280
Inborn errors of metabolism and the endocrinologist
ea0038p281
An unusual case of fish odour syndrome - tabloid paper helped in diagnosis?
ea0038p282
eGFR using CKD- EPI, MDRD and COCKCROFT - GAULT and glycaemic control among type 2 diabetics in an out-patient clinic in Nigeria
ea0038p283
Correlates of dysglycaemia and implications for diabetes care in Calabar, Nigeria
ea0038p284
Prevalence and risk factors for obesity among HIV patients in Kano, north western Nigeria
ea0038p285
Relationship between three indices of central obesity and fasting plasma glucose
ea0038p286
How well do front line healthcare professionals understand type 2 diabetes?
ea0038p287
Accuracy and reliability of glucose meters used at diabetes clinic of Oauthc Ile Ife
ea0038p288
Behavioural risk factors for diabetes mellitus: a study of secondary school staff in a community in south west Nigeria
ea0038p289
Influence of deuterium depleted water on indicators of prooxidant-antioxidant and detoxifying systems in experimental diabetes
ea0038p290
Renal function in type 2 diabetes patients at presentation in a tertiary hospital in Nigeria - a preliminary report
ea0038p291
Bloods glucose monitoring in diabetic inpatients - hyperglycaemia
ea0038p292
Case report of a type 2 DM patient with vitamin B12 deficiency anaemia
ea0038p293
Relationship between anthropometric indices and insulin resistance in Nigerians with type 2 diabetes mellitus
ea0038p294
Assessment of the relationship between obesity indices and lipid parameters among Nigerians with hypertension
ea0038p295
Hyperuricaemia and peripheral arterial disease in patients with diabetes mellitus
ea0038p296
Similia similibus curantur: using DPP-IV inhibitor to treat reactive hypoglycaemia
ea0038p297
Clinical profile of persons with diabetes attending an endocrinology clinic in a tertiary hospital in rural Nigeria
ea0038p298
Pituitary
A role for
11
C-methionine PET/CT-MRI in the management of
de novo
and residual acromegaly
ea0038p299
The effect of AIP on AHR transcriptional activity: implications for
AIP
mutations pathogenicity
ea0038p300
Investigation of the invasive phenotype of AIP-mutated pituitary adenomas
ea0038p301
Menin regulates the expression of miR-15a, which is downregulated and inversely correlates with cyclin D1 expression in mouse Men1-associated pituitary tumours
ea0038p302
An association between visual morphometric changes and psychiatric outcomes in patients with acromegaly
ea0038p303
The founder R304*
AIP
mutation is prevalent in Irish acromegaly and gigantism patients as well as in the general population of Ireland
ea0038p304
In vitro
effects of Imatinib on somatotrophinoma cell line
ea0038p305
Unique clinical picture in patients with X-linked acrogigantism
ea0038p306
Silencing of aryl hydrocarbon receptor protein (AIP) up-regulates the small Rho GTPase, CDC42
ea0038p307
Antisense oligomer therapy directed at the GH receptor is associated with reduction in circulating GHBP levels
ea0038p308
Developing a pituitary distress thermometer (PDT) - a means to improve patient quality of life
ea0038p309
Mortality of patients with non-functioning pituitary macroadenoma is significantly elevated: systematic analysis of 546 cases in a tertiary referral centre in the UK
ea0038p310
The burden of AIP mutations in pituitary adenoma patients from the UK
ea0038p311
ACTH and gonadotrophin deficiency predict mortality in patients treated for non-functioning pituitary adenomas (NFPAs) in the UK and Republic of Ireland: long-term follow-up of 519 patients across two tertiary referral centres
ea0038p312
A prospective observational study of the causation and management of SIADH in a tertiary referral hospital
ea0038p313
Biochemical assessment of disease activity in acromegaly; a comparison of single GH, GH day series mean, OGTT nadir and IGF-1 in 51 patients
ea0038p314
Expression of MGMT in a large series of pituitary adenomas: lactotroph and corticotroph adenomas are more likely to be MGMT-negative than somatotroph and gonadotroph adenomas
ea0038p315
Does basal post-operative early morning cortisol measurement predict HPA axis integrity as assessed by an insulin tolerance test in patients who have undergone pituitary surgery?
ea0038p316
Patient experiences of living with acromegaly in the UK
ea0038p317
An association between self-drawing, morphometric changes and psychological outcomes in patients with acromegaly vs non-functioning pituitary adenoma
ea0038p318
The accuracy of bilateral inferior petrosal sinus cannulation and usefulness of prolactin adjustment in one Scottish centre
ea0038p319
Neuronatin emerges in the rat pituitary stem/progenitor cells and terminates its role in the terminally differentiating cells
ea0038p320
Current clinical management of acromegaly in the UK; a survey of endocrinologists
ea0038p321
Traditional cardiac risk factors in a cohort of hypopituitary patients: a preliminary look at the utility of QRISK2 score
ea0038p322
Long term follow up of patients with craniopharyngioma
ea0038p323
Metabolic state in ACTH insufficient and ACTH sufficient patients with hypopituitarism not treated for growth hormone deficiency (GHD): a comparative study
ea0038p324
Using modified clamp study to replicate insulin stress test
ea0038p325
Impaired quality of life in patients with acromegaly despite long-term disease control: results from a longitudinal study
ea0038p326
Pituitary incidentaloma: features and outcomes: recent experience at a tertiary centre
ea0038p327
Development of a patient-reported outcome measure for pituitary surgery
ea0038p328
Management of pituitary apoplexy: the greater Manchester experience
ea0038p329
Feedback and GnRH pulse frequency decoding: a mathematical model for GnRH signalling in gonadotrophs
ea0038p330
Keep calm and give cabergoline: a giant prolactinoma presenting with seizures
ea0038p331
Loperamide-induced hypopituitarism
ea0038p332
An unusual case of pituitary pathology and the utility of whole body 18F-FDG PET-CT imaging in identifying extraneural biopsy targets
ea0038p333
Clinically non-functioning pituitary macroadenomas: presenting features and outcomes: recent experience at a tertiary centre
ea0038p334
Pituitary service review in a District General Hospital: a case for nationally agreed guidelines?
ea0038p335
A case of pituitary functional recovery in a patient with Langerhan's cell histiocytosis following chemotherapy with chlorodeoxyadenosine and mercaptopurine
ea0038p336
Unusual features in a case of hypophysitis following ipilimumab therapy
ea0038p337
Evolution in acromegalic patients with discordant GH-IGF1 levels during medical treatment
ea0038p338
Frontal bone recurrent ectopic craniopharyngioma after transfrontal resection: case report
ea0038p339
An unusual case of acromegaly
ea0038p340
How common is ipilimumab-induced hypophysitis leading to cortisol deficiency?
ea0038p341
TSH-secreting pituitary adenoma with negative TSH staining
ea0038p342
An unusual cause of headache in pregnancy
ea0038p343
The aggressive clinical course of silent corticotroph pituitary adenomas: a case series
ea0038p344
Intrasellar meningioma
ea0038p345
Silent corticotroph adenoma presenting with severe visual loss
ea0038p346
Reproduction
Analysis of the human foetal gonadal proteome at 13-14 weeks of gestation
ea0038p347
Development of a single-injection non-surgical sterilant via modification of measles virus pseudotyped particles
ea0038p348
Decoding gonadotrophin receptor signalling via spatial regulation of the LH receptor
ea0038p349
IGF1 action in trophoblast involves endocytic and post-endocytic pathways
ea0038p350
Intracrine androgens enhance decidualisation and modulate expression of human endometrial receptivity genes
ea0038p351
I.v. and s.c. infusions of kisspeptin-54 stimulate gonadotrophin release similarly in healthy women
ea0038p352
Assessment of reproductive parameters and oxidative stress following treatment with alcohol and/or cannabinol in male Wistar rats
ea0038p353
Increased expression of circulating miRNA-93 in women with polycystic ovary syndrome may represent a novel, non-invasive biomarker for diagnosis
ea0038p354
Vitamin D regulates extravillous trophoblast migration by inhibiting sphingosine-1-phosphate (S1P) signalling via S1P receptor 2
ea0038p355
Visceral fat drives 5[alpha]-reductase activity independent of BMI in women with polycystic ovarian syndrome
ea0038p356
Impact of male cholestasis on the sperm epigenome and consequences for the health of the offspring
ea0038p357
Isoform-specific knockdown of PKC isoforms reveals PKC[beta]2 is required for epidermal growth factor stimulated expression of the prostaglandin synthase COX2 in human myometrium
ea0038p358
Information transfer in GnRH signalling: ERK-mediated feedback loops control hormone sensing
ea0038p359
Whole exome sequencing in congenital hypogonadotropic hypogonadism
ea0038p360
Implantation and pregnancy outcome of rats fed with low and high salt diet
ea0038p361
Vitamin D metabolic profiling across pregnancy
ea0038p362
Vitamin D and foetomaternal immunity: effects on uterine natural killer cells
ea0038p363
Use of an animal model to identify the origin and validity of the testicular dysgenesis syndrome hypothesis in humans
ea0038p364
Investigation into the effects of glucocorticoids in a mouse model of induced menstruation
ea0038p365
Structured education programme to improve cardiovascular risk in women with polycystic ovary syndrome: SUCCESS-RCT improved physical activity and illness perception
ea0038p366
Characterisation of a GnRH-type signalling system in an echinoderm
ea0038p367
Low-dose gonadotrophin therapy for induction of ovulation: comparison of results in women with PCOS or hypothalamic amenorrhoea
ea0038p368
Characterisation of bile acid pathways in steroidogenic tissues
ea0038p369
Food, drink and medical plants and their molecules can affect female hormones and reproductive functions
ea0038p370
Regulation of Cyp17a1 expression in mouse ovarian theca cells in vivo and in vitro
ea0038p371
Maternal insulin-like growth factor-1 and transforming growth factor beta-1 levels during pregnancy in rats fed with low and high salt
ea0038p372
Identification of novel transcription factors that may regulate transcription of the equine chorionic gonadotrophin beta subunit
ea0038p373
A rare form genetic abnormality in Turner syndrome
ea0038p374
Long-term monitoring of hypogonadal men receiving intramuscular testosterone replacement: a retrospective audit
ea0038p375
Prevalence and correlates of premature ejaculation among Nigerians in a tertiary health centre: a preliminary cross-sectional study
ea0038p376
Effects of oral, injectable, and implant hormonal contraception on serum levels of iron, ferritin, copper, ceruloplasmin and vitamin E
ea0038p377
Importance of social support and implications of gender reassignment in congenital adrenal hyperplasia due to 3-[beta] hydroxysteroid deficiency
ea0038p378
Testicular regression syndrome and severe psychiatric disorder - a rare association preventing the optimal management of the endocrine condition
ea0038p379
Self medication in transpeople is not associated with deterioration in cardiovascular risk factors but is associated with reduced vitamin D levels and antidepressant use
ea0038p380
A pragmatic review of patient satisfaction and testosterone replacement therapy
ea0038p381
Spontaneous resolution of hypothalamic amenorrhea post diagnostic GnRH test
ea0038p382
Steroids
Adrenocortical function in glucocorticoid receptor deficient mice
ea0038p383
TNF[alpha] regulates steroid sulphatase activity in healthy and malignant tissue
ea0038p384
Genome-wide binding analysis of glucocorticoid receptors in the rat hippocampus in response to corticosterone and stress
ea0038p385
Impact of 5[alpha]-dihydrotestosterone (DHT) on glandular epithelial proliferation in the mouse uterus
ea0038p386
Plasma corticosteroid-binding globulin: biomarker of inflammation onset and severity in a rat arthritis model
ea0038p387
A novel animal model to explore the whole-organism response to 21-hydroxylase deficiency
ea0038p388
Regulation of glucocorticoid receptor action by ARID subunits of the SWI/SNF complex
ea0038p389
Alpha-MSH secretion from a gastro-intestinal stromal tumour leading to ACTH-independent Cushing's syndrome
ea0038p390
Involvement of the TORC isoforms in adrenal responsiveness to basal and stress-induced HPA activity
ea0038p391
Exploring metabolomic changes due to cortisol deficiency in early development using the ferredoxin (fdx1b) null-allele zebrafish
ea0038p392
The effects of chronic administration of the synthetic glucocorticoid dexamethasone on memory and learning in the rat
ea0038p393
Synthetic glucocorticoid (GC) treatment induces prolonged activation of GC receptors in discrete brain regions and impairs memory and learning processes in the rat
ea0038p394
Vitamin D2 vs vitamin D3: effects of total and free 25-hydroxyvitamin D on immune cells
in vivo
ea0038p395
Model systems to define the role of AKR1D1 in metabolic liver disease
ea0038p396
Molecular and immunohistochemical analysis of aldosterone producing adenomas
ea0038p397
Discrimination of adrenocortical carcinoma from other adrenal lesions: use of a new 13 steroid serum panel based on LC-MS/MS
ea0038p398
Glucocorticoid-induced lipolysis across human ageing and the relationship to fat mass and androgens
ea0038p399
Rapid equilibriation of cortisol between the free and total plasma pools
ea0038p400
Do androgens lead to increased erythropoiesis in women with congenital adrenal hyperplasia?
ea0038p401
Bioinformatic analysis of microRNAs associated with aldosterone secretion
ea0038p402
Immunogenicity in AAD patients treated with depot tetracosactide
ea0038p403
Unveiling the complexity of the undifferentiated zone in the human adrenal cortex
ea0038p404
Cytosolic innate immune receptor RIG-I amplifies glucocorticoid action within lung epithelial cells
ea0038p405
Quantitative analysis of an adrenal steroid profile, canrenone, and mifepristone in plasma by triple quadrupole mass spectrometry
ea0038p406
Conventional vs modified release hydrocortisone in mitotane treated patients with adrenocortical cancer
ea0038p407
Effects of diet and gender on postprandial salivary glucocorticoid levels and bile acid excretion in healthy volunteers
ea0038p408
Shocking? A systematic review of adrenal insufficiency in adults on oral steroids
ea0038p409
Hormone replacement therapy with prednisolone in adrenal insufficiency patients: data from the European Adrenal Insufficiency Registry (EuAIR)
ea0038p410
The effect of adrenalectomy on cardiovascular morbidity in adrenal tumor patients with subclinical Cushing's syndrome: systematic review and meta-analysis
ea0038p411
DHEA reduces the palmitate-induced apoptosis in L6 myotubes
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Profiling of multiple vitamin D metabolites in a healthy human cohort by high-throughput liquid chromatography-tandem mass spectrometry analysis
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Support from clinical audit data for liberal minimum 0900 h cortisol cut-off to avoid short Synacthen tests
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Lineage conversion of human cells to an adrenocortical phenotype: a new technology to study the adrenal gland
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Steroid-dependent patients with multiple co-morbidities are more vulnerable to adrenal crisis
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Comorbidities are the norm for steroid-dependent patients and predispose to adrenal crisis
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Lack of awareness contributes to delayed diagnosis and inappropriate management in men with low testosterone: findings from a UK study of men diagnosed with hypogonadism
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Heterogeneity in the clinical management of adrenal insufficiency - data from EU-AIR
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Phaeochromocytoma related reversible Takotsubo cardiomyopathy
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Iatrogenic Cushing's syndrome secondary to combined oral contraceptive pill in a patient with congenital adrenal hyperplasia
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Bilateral adrenal haemorrhage in a patient with anti-phospholipid syndrome
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Transient adrenal insufficiency following acute bilateral adrenal haemorrhage
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X-linked adrenoleukodystrophy - how to improve identification in the Addison's population
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Primary testicular lymphoma with bilateral adrenal masses and adrenal insufficiency
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Adrenal insufficiency from bilateral adrenal haemorrhage in a postoperative patient on warfarin
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Cushing's syndrome secondary to bilateral functioning adrenocortical adenoma
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Complications of CAH in pregnancy
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Liquorice induced hypermineralocorticoidism - a case report from Midyorkshire Hospitals NHS trust
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Autoimmune polyendocrine syndrome type 4
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A severe case of ectopic ACTH presenting with Cushing's syndrome with hypokalaemia, hypomagnesemia, hypophosphatemia, hyponatraemia and hypocalcaemia
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Thyroid
Peripheral blood microRNA markers in patients with papillary thyroid cancer
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Effect of hypothyroidism on pancreatic [beta]-cell mass and circulating insulin concentration in the ovine foetus
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Thyroid hormones and mitochondrial development in skeletal muscle of foetal sheep near term
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The natural history of subclinical hyperthyroidism due to Graves' disease
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Epitopes, specificity, functional effects, and IgG subclasses of anti-calcium-sensing receptor autoantibodies in patients with autoimmune polyendocrine syndrome type 1
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Reliability of thyroid ultrasounds in assessment of thyroid nodules
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Subclinical and overt hypothyroidism in pregnancy: what happens next?
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Soy protein with isoflavones impairs thyroid function
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Increased rehospitalisation rate and cardiovascular morbidity in inpatients with hyperthyroidism - a matched case-control study
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Small fibre dysfunction in hypothyroidism - a prospective study using methods of small fibre function and structure
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A cross-sectional survey to determine iodine status of school girls living in Northern Ireland
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Thyroid abnormalities during anti-PD1 cancer immunotherapy
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The effect of isoflavone-free soy protein supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: a randomised double blind crossover study
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A cross sectional survey of dietary iodine intake in pregnant women living in Northern Ireland
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Is one benign thyroid FNA cytology sufficient to out rule malignancy? A university teaching hospital experience
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The value of second fine needle aspiration cytology tests when investigating benign thyroid nodules (Thy2/Thy2c)
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Management of amiodarone induced thyrotoxicosis within the United Kingdom: is it time for a consensus guideline? A single centre retrospective review
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Serum thyroid stimulating hormone concentration after withdrawal of thionamides as a predictor of Graves' disease outcome
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Maternal thyroid function in pregnancy and risk of breech presentation
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Ultrasound guided thyroid FNA with cytopathology in-attendance significantly improved accuracy in a university teaching hospital
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Diagnostic and therapeutic challenges in medullary thyroid carcinoma
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Less is more: superior efficacy and tolerability of 400 MBq radioactive iodine for management of thyrotoxicosis
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Incidental thyroid malignancy in Grave's thyrotoxicosis
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Management of thyroid cancer: a 5-year retrospective audit
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Thyroid eye disease audit - the Wolverhampton experience
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R438H missense mutation related generalised resistance to thyroid hormone (GRTH): a case series report in three generations
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Imaging in subclinical hyperthyroidism: findings from a single centre cohort
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Qualitative analysis of ultrasound reports assessing radiological descriptors of thyroid nodules - a retrospective pilot audit
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An audit of hyperthyroidism in pregnancy
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Thyroxine administration: a challenging case
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Thyroid deficiency refractory to treatment: is this a case for DOT?
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Recurring thyroid eye disease: a diagnostic dilemma
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Timing of food intake and L-thyroxine replacement - a cost saving simple change of phrasing in the British National Formula
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The value of thyroxine absorption test followed by weekly thyroxine administration in determining the cause of persistent hypothyroidism despite high dose
L
-thyroxine treatment: a case report
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Resistance to thyroid hormone in a family of Bangladeshi extraction
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More than meets the eye: a case of longstanding hypothyroidism due to Hashimoto's thyroiditis presenting with unilateral thyroid eye disease
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TSH receptor antibodies testing in hypothyroid pregnant women
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Thyroid dysfunction secondary to antiviral therapy: a simple management protocol
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Case report: propylthiouracil-induced ANCA-associated-vasculitis
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Odd TFTs: when it does not fit, it probably is not right!
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Primary radioactive iodine ablation for TSH secreting adenoma - an uncommon treatment for a rare disease
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An unusual cause of hypercalcaemia
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Buying time: a unique case of delayed thyroidectomy post thyroid storm
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A disputable but effective therapy in neutropenia associated with Graves' disease
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Late stage Hashimoto's or Riedel's? A case report illustrating this diagnostic conundrum
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Investigating pyrexia whilst awaiting thyroidectomy for Thy 3, Hurthle cell neoplasia
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The roller-coaster ride of thyroid function before, during and after pregnancy
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Metastatic differentiated thyroid cancer with undetectable serum thyroglobulin: diagnostic, management and follow-up challenges
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Thionamide resistant Graves' disease - it's not always poor compliance
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Recurrent Hashimoto's encephalopathy: a case report of reversible coma and status epilepticus
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Hyperthyroidism in an elderly patient intolerant to carbimazole
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Radioiodine therapy in benign thyroid disease
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Severe myxoedema complicated by peri-orbital oedema, gum oedema, SIADH and ECG changes
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Inadequate TSH - resistance to thyroid hormones: two case reports
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Management of hypothyroidism in pregnancy with armour thyroid
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A case of thyroid hormone resistance with unusually elevated free thyroxine
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Hypercalcaemia: look beyond the usual
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If it feels like myxoedema coma, then it probably is!
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Preoperative parathyroid imaging: a retrospective audit
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