Endocrine Abstracts

Multiple endocrine neoplasia (MEN) syndromes are rare autosomal-dominant disorders that predispose affected individuals to benign and malignant tumours involving two or more endocrine glands. Four major forms of MEN are recognised, each associated with the occurrence of specific tumours. MEN1 is due to germline-inactivating mutations of the MEN1 tumour-suppressor gene, and is associated with the occurrence of parathyroid, pancreatic islet and anterior pituitary tumours. MEN2 (...

Genetic testing plays an increasing role in diagnosing and managing patients with Multiple Endocrine Neoplasia (MEN). Advances in genetic testing technology, combined with a fall in the cost of analysis, provides the opportunity to test more patients as early as possible, to try to confirm or refute whether there is a genetic variant contributing to their endocrine neoplasia. If a MEN syndrome is confirmed genetically, then ongoing management and surveillance can be tailored, ...

Working with individuals and families with a complex and unpredictable genetic condition like MEN can present particular challenges for health professionals. This session will aim to support you in supporting your patients by focusing upon the psychological aspects of living with MEN....