The founder R304* AIP mutation is prevalent in Irish acromegaly and gigantism patients as well as in the general population of Ireland
1Department of Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, London, UK; 2Department of Endocrinology, C. Davila University of Medicine and Pharmacy and C.I Parhon National Institute of Endocrinology, Bucharest, Romania; 3Research Department of Genetics, Evolution and Environment, University College London, London, UK; 4Department of Medical Genetics, Belfast HSC Trust, Belfast, UK; 5Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Belfast, UK; 6Department of Molecular Genetics, Royal Devon and Exeter Foundation Trust, Exeter, UK; 7Department of Endocrinology and Diabetes, Beaumont Hospital/RCSI Medical School, Dublin, Ireland; 8Department of Clinical Medicine and Institute of Molecular Medicine, Trinity College Dublin, Trinity Centre for Health Sciences, St Jamess Hospital, Dublin, Ireland; 9Royal Belfast Hospital for Sick Children, Belfast, UK; 10Endocrinology Service/Experimental Endocrinology Unit, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico; 11Barnet General Hospital, London, UK; 12Academic Endocrine Unit, University of Oxford, Oxford, UK; 13University College London Hospitals, London, UK; 14University of Michigan, Ann Arbor, MI, USA; 15Department of Endocrinology, University Hospitals of Leicester, Leicester, UK; 16Department of Endocrinology, St Jamess University Hospital, Leeds, UK; 17Institute of Anthropology, Johannes Gutenberg University, Mainz, Germany; 18North East Thames Regional Genetics Service, Great Ormond Street Hospital, London,UK; 19Trinity Biobank, Institute of Molecular Medicine, Trinity College Dublin, Trinity Centre for Health Sciences, St Jamess Hospital, Dublin, Ireland; 20Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queens University Belfast, Belfast, UK; 21Schools of Biosciences and of Mathematics & Statistics, University of Melbourne, Australia; 22Centre for Cancer Research and Cell Biology, Queens University Belfast, Belfast, UK.
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