Endocrine Abstracts (2016) 41 EP1082 | DOI: 10.1530/endoabs.41.EP1082

Clinical and epidemiological profile of patients with hyperthyroidism and hypothyroidism that receive endocrinological services from a medical institution in Medellin (Colombia) between 2013 and 2015

Paula Velásquez, Felipe Osorio, Sergio Ramírez, Laura Jaramillo, Juliana Molina, María de los Ángeles Rodríguez & Lina Martínez

Universidad Pontificia Bolivariana, Medellin, Antioquia, Colombia.

Introduction: Endocrine Illnesses have high prevalence on a global level due to multiple etiologies that can lead alterations to this system.

Objective: Determine the epidemiological profile of hyperthyroid and hypothyroid patients that receive endocrinological services from a medical institution in Medellin (Colombia) between 2013 and 2015.

Methodology: A descriptive, retrospective study was conducted and included the clinical records of patients diagnosed with hyperthyroidism or hypothyroidism. A univariate analysis was applied using descriptive statistics by means of absolute frequencies and proportions in the SPSS software, version 19.0.

Results: A sample was obtained with 131 patients with hypothyroidism and 18 with hyperthyroidism, the average age was 56.7±17.8 years and 55.6±15.1 years, respectively. The frequency of female sex with hypothyroidism was greater than those patients with hyperthyroidism (86.3% versus 66.7%). Post-surgery hypothyroidism had a high prevalence (11.5%) followed by the Hashimoto disease (5.3%). The principal etiologies in hyperthyroidism were Graves disease (33.3%) and thyrotoxicosis (22.2%). With relation to the signs and frequent symptoms in the studied patients, the goiter was common in 14.5% of the patients with hypothyroidism versus 38.9% of those patients with hyperthyroidism. The most frequent diseases on past medical history in both groups of patients were high blood pressure and Diabetes Mellitus.

Conclusion: The results align with what is described in the literature of both pathologies, being more common in women with primary gland disfunction. In relation to classic symptoms of the disease such as fatigue and adynamia, neither were the most relevant in this study.

Keywords: Thyroid Diseases, Hypothyroidism, Hyperthyroidism, Goiter