Endocrine Abstracts

Hyperandrogenism in adolescent girls is medical and social problem, including hirsutism, seborrhea, severe acne, alopecia and hyperclitoridism.

Purpose: To study the frequency and clinical peculiarities of the hyperandrogenism (HA) in adolescent girls.

Patients and methods: The study included 2369 girls (aged 11–19 years). Patients were subjected to the clinical examination, ultrasound examination. Index of hyperandrogenism (HAI) were calculated (the Ferriman–Gallwey score).

Results: The investigation shows that 341 (14%) girls had HA. In 100% adolescents with HA had acne, seborrhea and menstrual disorders. Results showed that dysmenorrhea (99%) and hypermenstrual syndrome (80%) highly prevalent among patients with HA. Girls with HA observed median Ferriman–Gallwey scores of 13 (range: 7–18). The macromastia was found in 20 (9%), breast hypoplasia in two girls. The dysplasia of mammary glands (mastopathy) was diagnosed in all patients with macromastia. The morbid obesity (BMI≧40 kg/m²) was diagnosed in 26 (8%) girls with HAI >12. In 99% adolescents with HA was found ultrasound signs multifollicular ovaries, in two girls had ultrasound signs polycystic ovary syndrome.

Conclusions: This study has shown that HA have been diagnosed in every tenth adolescent girls. The clinical features in girls with HA were hirsutism, menstrual disorders and multifollicular ovaries. The multifollicular ovaries in adolescents are indication for observation.