ea0044p200 | Reproduction | SFEBES2016
, Zhang Yuehui
, Hu Min
, Billig Hakan
Peripheral insulin resistance and hyperandrogenism are the primary features of polycystic ovary syndrome (PCOS). However, how insulin resistance and hyperandrogenism affect uterine function and contribute to the pathogenesis of PCOS are open questions. Rodent models of insulin and human chorionic gonadotropin (hCG) treatment have provided systems in which to study ovarian insulin resistance, ovarian stromal hyperplasia, follicular cyst formation, and impaired mitochondrial fun...