Searchable abstracts of presentations at key conferences in endocrinology
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19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

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20-23 May 2017, Lisbon, Portugal Further information

Eposter Presentations: Interdisciplinary Endocrinology

Diabetes (to include epidemiology, pathophysiology)

ea0049ep776 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Diagnosis of cystic fibrosis related diabetes

Rebollo-Roman Angel , Moreno-Moreno Paloma , Barrera-Martin Ana , Herrera-Martinez Aura-Dulcinea , Vaquero-Barrios Jose-Manuel , Calanas-Continente Alfonso

Aim: To describe the prevalence of abnormal glucose tolerance and diabetes in patients with cystic fibrosis (CF) depending on the diagnostic criteria.Methods: Observational, cross-sectional, clinical research on patients with CF evaluated at Hospital Universitario Reina Sofía (Córdoba).Results: Twenty-eight patients were selected for the study. Age: 31.85±8.78 years, with a CF evolution time of 21.77±9.37 years....

ea0049ep777 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Erk- and Akt-mediated osteocalcin signaling in human pancreatic β-cells does not directly involve GPRC6A activation

Perego Silvia , Sansoni Veronica , Faraldi Martina , Banfi Giuseppe , Lombardi Giovanni

Osteocalcin (OC) is the main non-collagenous protein of the bone and it has a regulatory role in mineralization. Extra-skeletal roles have been recently hypothesized for OC (e.g., modulation of glucose-induced insulin secretion by interacting with GPRC6A in β-cells). However, OC-mediated GPRC6A activation has been demonstrated only in rodents and heterologous systems. In this study we aimed at evaluating the dose-dependent response to OC and the eventual activation of the...