Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2017) 49 EP1251 | DOI: 10.1530/endoabs.49.EP1251

ECE2017 Eposter Presentations: Thyroid Thyroid (non-cancer) (260 abstracts)

The challenge of diagnosing thyroid storm: a comparison of the Japanese Thyroid Association Criteria to de Burch Wartofsky Point Scale

María Laura García 1 , Gabriela Szuman 1 , María Florencia Scoscia 1 , Susana Bacigaluppi 1 , María Victoria Panebianco 3 & Noelia Rella 1,

1Sanatorio Méndez, Buenos Aires, Argentina; 2Hospital Británico, Buenos Aires, Argentina; 3CEBBAD, Universidad Maimonides, Buenos Aires, Argentina.

Thyroid storm (TS) is a rare and life threatening condition that requires a prompt recognition and treatment. The clinical features may overlap with other acute medical conditions. Currently both Akamizu Criteria (JTA) and Burch and Wartofsky Scale (BW) are helpful diagnostics tools.

Objective: To evaluate TS patients according to currently available criteria and to identify the clinical features and outcomes.

Methods: A single center retrospective study covering a 6 year period was performed.

Results: Fifteen cases were identified, resulting in four cases of TS per 10 000 admitted. Mean age 49.8±17.3 years (range: 31–86). Male/Female: 3/12. Etiology: autoimmune (n=8), factitious (n=3), amiodarone-induced (n=3), undetermined (n=1). Manifestations at admission: cardiovascular (n=8), fever (n=3), delirium (n=2), diabetic ketoacidosis (n=1) and hypokalemic paralysis (n=1). Eleven had previous history of thyroid disease. Precipitating factors were found in 12 cases. Thyroid hormone levels did not correlate with the severity of thyrotoxicosis. Mortality rate was 6.6%: 1 patient died from sepsis. Late hospital discharge was found in 4 patients (P=0.01): 3 required antithyroid drugs withdrawal and the other received a heart transplant. The table resumes patients according to BW and JTA. JTA fails to detect 4 patients with impending TS (st0), one of which later on developed st1 (p8).

Conclusions: Ours results shows discrepancies between the two diagnostic systems. BW appears to select a higher percentage of patients for aggressive therapy than JTA. This presentation provides useful information for the management of TS, a rare and acute disease that requires high clinical suspicion in order to improve patient survival.


Volume 49

19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

European Society of Endocrinology 

Browse other volumes

Article tools

My recent searches

No recent searches.