Searchable abstracts of presentations at key conferences in endocrinology
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19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

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20-23 May 2017, Lisbon, Portugal Further information

Symposia

Hyperandrogenism: challenges in clinical management

ea0049s18.1 | Hyperandrogenism: challenges in clinical management | ECE2017

Hyperandrogenic states: pitfalls in diagnostic approach

Pugeat Michel

Measuring total testosterone level is the first line approach to assess androgen excess in women. Most laboratories in Europe use direct testosterone immunoassay without prior extraction. In the near future, liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) will be commonly used for measuring testosterone, providing the best accuracy with low limit of detection. In all cases, testosterone norms must be standardized for normal premenopausal women values. Wh...

ea0049s18.2 | Hyperandrogenism: challenges in clinical management | ECE2017

Metabolic perspectives for the non-classical CAH (NCAH)

Kelestimur Fahrettin

Congenital adrenal hyperplasia (CAH) is one of the most common autosomal recessive inherited endocrine diseases and is characterized by complete or partial impairment of adrenal steroidogenesis. 21-hydroxylase deficiency and 11β-hydroxylase deficiency account for 90% and 6–8% of cases of CAH, respectively. NCAH is the mild form of CAH and occurs in approximately 0.1–0.2% in the general population. The worldwide prevalence of NCAH among hyperandrogenic women is a...

ea0049s18.3 | Hyperandrogenism: challenges in clinical management | ECE2017

Hyperandrogenism and cardiometabolic risk

Pfeifer Marija

Hyperandrogenism is the main characteristic of PCOS therefore hyperandrogenism in women is best addressed when studying this highly prevalent syndrome. Besides the clinical features of oligomenorrhea, hirsutism and infertility, PCOS patients are often insulin resistant (IR), obese, they have arterial hypertension, dyslipidemia, an increased pro-thrombotic state, impaired glucose tolerance or frank type 2 diabetes (T2D). The prevalence of metabolic syndrome is doubled as compar...