Endocrine Abstracts (2017) 49 EP569 | DOI: 10.1530/endoabs.49.EP569

Diabetic choroidopathy and renal function

Antonio Manuel Garrido Hermosilla1,2, Mariola Méndez Muros3, Cristóbal Morales Portillo3, Tomás Martín Hernández3, Natividad González Rivera3, María Jesús Díaz Granda1,2, Enrique Rodríguez de la Rúa Franch1,2 & Estanislao Gutiérrez Sánchez1,2


1Ophthalmology Department, Virgin Macarena University Hospital, Seville, Spain; 2OftaRed – RETICS Ocular Pathology, Institute of Health Carlos III, Madrid, Spain; 3Endocrinology Department, Virgin Macarena University Hospital, Seville, Spain.


Objectives: Examine the relationship between choroidal thickness (CT) and renal function tests.

Methods: Cross-sectional study with 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic and ocular data were analyzed as well as the following renal function tests: microalbuminuria, microalbumin/creatinine ratio and glomerular filtration rate (CKD-EPI and MDRD-4). Choroidal thickness was measured by swept-source ocular coherence tomography (SS OCT).

Results: The mean age was 49.76±17.61 years old (18–74), with a sex ratio of approximately 1:1. 66.7% suffered from type 2 diabetes mellitus, with a mean time of evolution of 12.14±10.08 years. 51.2% of patients didn’t present diabetic retinopathy. Among renal function tests, only microalbuminuria positively correlated with CT (P<0.05).

Conclusions: The analysis of CT with SS OCT could be a prediction tool of renal function in diabetic patients.

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