ECE2017 Eposter Presentations: Adrenal and Neuroendocrine Tumours Adrenal cortex (to include Cushing's) (86 abstracts)
Aim: The aim of the study was to evaluate the correlation between salivary and serum cortisol values to the healthy people and patients with Cushings syndrome.
Methods: 33 cases: 21 healthy people aged 22 to 53 years old; 12 patients with Cushings syndrome values were included to our study. All the participiants of control group were healthy without known disease. Two samples of salivary and serum cortisol was taken to all the participiants of the study in the morning and in the midnight. All the subject respect the rolls of salivary collected samples.
Results: The mean age of the healthy subjects was 31±4.8 years old. Basal salivary cortisol was significantly correlated with serum salivary cortisol in the morning and at the midnight; P<0.05 in the morning and P=0.052 at the midnight. Pearson coefficients were 0.45 in the morning and 0.42 at the midnight (2300 h). The sensitivity of salivary cortisol values in diagnoses of Cushings syndrome was 100% for cut off values 2.18 ng/dl and for cut off values 3.14 ng/dl the sensitivity was 100% and specificity 83%. ACU 0.97.
Conclusions: In our study we found a correlation between salivary and serum cortisol values in both samples, at the morning and at the midnight to all participants; in healthy people, patients with Cushings disease.
Keywords: salivary cortisol; serum cortisol; correlation
20 May 2017 - 23 May 2017