Endocrine Abstracts

Objectives: The objective of our – investigation is to find out the role of D3 vitamin deficiency – and calcium in patients with autoimmune thyroiditis and calcified nodules.

Methods: The research has been carried out at “Muratsan” University Hospital and “Armenia” Medical Center, in 2013–2016.

80 patients (ages ±4–0, of which 68 women and 12 men) with autoimmune thyroiditis and calcified nodules have taken part in the clinical research.

They have been tested on TSH, FT4, anti-TPO, vitamin D3, Ca²⁺, PTH, as well as undergone a thyroid ultrasound, elastography.

Results: TSH – 58%↑, 42% N

FT4 – 60% ↓, 40%N

Anti-TPO – 100%↑

Vitamin D3 – 84%↓, 16%N

Ca²⁺ – 94%N, 6%↓

PTH – 89% ↑, 11%N

Thyroid ultrasound – Calcificates proved to be present in 76% of nodules, which have been formed on the background of autoimmune thyroidits.

Thyroid elastography after 6 month taking vitamin D3 13% 3b elastography is go to 3a. The increased level of PTH hormone and lower vitamin D3 should be taken into consideration, since this can result from secondary hyperparathyroidism and cause formation of calcificates.

Conclusions: Vitamin D3 shout be tested in the first place during the treatment of any kind of calcified nodular goiter, since calcificates can be caused not only by oncologic processes, but also secondary hyperparathyroidism.