ECE2017 Eposter Presentations: Diabetes, Obesity and Metabolism Diabetes complications (102 abstracts)
A rare presentation of diabetic ketoacidosis: Rhino-orbito-cerebral mucormycosis
Askin Gungunes 1 , Senay Arikan Durmaz 1 , Selim Yalcin 2 , Aydin Cifci 3 , Veysel Burulday 4 & Ayse Carlioglu 5
1Department of Endocrinology and Metabolism, School of Medicine, Kirikkale University, Kirikkale, Turkey; 2Department of Oncology, School of Medicine, Kirikkale University, Kirikkale, Turkey, 3Department of Internal Medicine, School of Medicine, Kirikkale University, Kirikkale, Turkey; 4Department of Radiology, School of Medicine, Kirikkale University, Kirikkale, Turkey; 5Department of Internal Medicine, Erzurum Regional Training and Research Hospital, Erzurum, Turkey.
Aim and objective: Mucormycosis is a rare life-threatening fungal infection. Immunocompromised patients are often affected. We report a rare diabetic patient with pancreatic adenocarcinoma who was presented diabetic ketoacidosis and rhino-orbito-cerebral mucormycosis.
Case presentation: A 66 years old man with pancreatic adenocarcinoma and type 2 diabetes mellitus was presented diabetic ketoacidosis and severe infection of the facial sinuses, orbita, and soft palate in the right half of the face. It was learned that the infection developed after tooth extraction. Diabetic ketoacidosis improved after fluid and electrolyte replacement and insulin treatment. Non-septate hyphae structures were shown in biopsy sample from affected tissues. Brain MRI showed that this infection was extended to the brain. Amphotericin B therapy was started immediately due to delay rapid progression and recommended surgical debridement. Surgical debridement is the main therapy for mucormycosis but patient and his relatives did not accept surgical treatment. Amphotericin B therapy was continued but he dead within the following 2 months.
Conclusion: In diabetic patients with impaired immunity, procedures such as tooth extraction can cause rare serious infections like mucormycosis.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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