Endocrine Abstracts (2017) 49 EP553 | DOI: 10.1530/endoabs.49.EP553

Atherosclerotic cardiovascular risk assessment score in diabetes patients: a retrospective analysis of clinical data

Sanjiv Shah, Jayaprakashsai Jana, Balaji Jaganmohan, Raja Selvarajan, SG Moazam, Vamsi Krishna Kolukula, Surekha Tippisetty & Shashank R Joshi

Apollo Sugar Clinics, Hyderabad, India.

Background: The study aimed to minimize the risk causing factors and evaluate new atherosclerotic cardiovascular disease (ASCVD) risk score using Million Hearts® Longitudinal ASCVD risk assessment tool among type 2 diabetes mellitus (T2D) patients.

Methods: A non-interventional retrospective analysis of electronic medical records of Apollo Sugar Clinics, India. A total of 365 patient’s data was collected, and were categorized into normotensive (<120-129/80, mmHg), prehypertensive (130-139/80-89, mmHg), and hypertensive (>140/90, mmHg) based on their blood pressure (BP). ASCVD risk score of each patient was calculated using Million Hearts® Longitudinal ASCVD Risk Assessment Tool, as per ACC/AHA 2016 guidelines. Statistical analysis was done by using SPSS version 20, with significance set at 2 tailed P ≤0.05.

Results: Total 365 patients were analysed, their mean (SD) age was 52.6 (11.9) years, 63.6% were males and 36.4% were females. Of these patients 45.8%, 24.4%, and 29.9% were normotensive, prehypertensive, and hypertensive, respectively. The indicators of ASCVD risk, age, BMI, and total cholesterol (each P<0.05) were significantly different among three groups. Of the 365 patients only 161 patients who met the ASCVD risk assessment criteria the score was calculated. The 10-year baseline risk score was 16.8% and expected risk would reduce to 12.5% if statin therapy is initiated. A significant difference in risk score was observed among three groups at baseline (14.4%; 15.6%; 19.4%, P=0.05), and expected 10-year risk (10.8%; 11.6%; 14.4%, P=0.07) if statin therapy initiated.

Conclusion: Treatment of cholesterol level by moderate or high intensity statins should be an essential component of multifactorial intervention for primary prevention of CV disease in diabetes patients.

Article tools

My recent searches

No recent searches.