Endocrine Abstracts (2017) 49 EP664 | DOI: 10.1530/endoabs.49.EP664

Assessment of adipose tissue distribution in youg women with polycystic ovary syndrome

A Savchanka & Tatjana Mokhort

Belarussian State Medical University, Minsk, Belarus.

PCOS is characterized by abdominal obesity along with conventional diagnostic features.

Objective: To assess body composition in women with PCOS and normal body weight.

Materials and methods: 35 women (24±1.1 years old) with confirmed diagnosis of PCOS according to Rotterdam criteria, 27 almost healthy women (25±1.2 years old), both groups wotn normal weight. Whole Body Dual-energy X-ray Absorptiometry (DEXA Total Body) scans were carried out using ‘Prodigy Lunar’ machine (USA).

Results: Registered differences included increase of total fat accumulation, fat accumulation in android compartments as well as android-gynoid fat ratio index. Basic antropometric measurements and DEXA of patients with POCS and control group. 29 (82.86%) patients in study group demonstrated significantly higher waist circumference (77.1±11.2 cm) and higher percentage of adipose tissue in android area (37.9±3.0%) correspondingly compared to control group (R – 0.846176 at P <0.05).

Table 1
MeasurementsStudy group, n=35Control group, n=27
Total fat content, g 34.257±5.763 17.737±2.393
Total fat content by DEXA, %37.3±6.7. P<0.0529.2±4.9
Trunk fat accumulation, g11.315±3.4006.326±1.592
Trunk fat accumulation, %31.2±4.729.3±2.7
Fat accumulation in android compartments, %37.9±3.0, P<0.0530.9±3.1
Fat accumulation in gynoid compartments, %40.5±4.339.3±2.8
Android-gynoid fat ratio index (A/G) 0.91±0.1, P<0.050.76±0.1

Conclusion: Abdominal fat accumulation is attributable to patients with PCOS. Lack of significant differences between BMI and total fat accumulation is apparently explained by age, dietary habits, patient’s disease awareness as well as reasonable life style modification and physical exercises modification.

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