Endocrine Abstracts

Congenital gonadotropin-releasing hormone deficiency is a rare disorder characterized by incomplete or absent puberty and infertility. This condition is both clinically and genetically heterogeneous and presents with a broad spectrum of phenotypes ranging from mild to severe. This presentation will provide a review of hypogonadotropic hypogonadism, including the clinical presentation of HH, a rational approach to evaluating HH patients, and an update on treatment options. In particular, the speaker will focus on the choice of the most appropriate treatment in hypogonadotropic hypogonadism based on clinical presentation including the use of rFSH to enhance treatment outcome.