Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology BES 2017

Harrogate, UK
06 Nov 2017 - 08 Nov 2017

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SfE BES 2017 will be on the 6-8 November 2016 in Harrogate, UK.

ePoster Presentations

Clinical Biochemistry

ea0050ep041 | Clinical Biochemistry | SFEBES2017

Sertraline-induced non-hyperinsulinemic hypoglycaemia in a non-diabetic patient : A case report

Karim Rehmat , Shah Najeeb , Jadoon Nauman , Mohammed Kamrudeen

Case: A 44-year-old patient presented with symptoms of sweating, shaking and hunger, which were all eased by eating. Her symptoms were suggestive of hypoglycaemia, experienced predominantly 2-3 hours after meals. Hypoglycaemia was confirmed during these episodes. She had normal liver and renal function. There was no history of Diabetes Mellitus.Her symptoms improved slightly with measures of adjusting her diet but did not sett...

ea0050ep042 | Clinical Biochemistry | SFEBES2017

A rare cause of acute severe hyponatraemia secondary to the syndrome of inappropraite anti-diuretic hormone (SIADH) secretion

Wordsworth Georgina , Hasan Faisal , Parfitt Vernon , Chau Fong , Cheyne Elizabeth , Tatovic Danijela , Lonnen Kathryn , Johnson Andrew

Hyponatremia is the commonest electrolyte abnormality presenting to Medical Admissions and when acute, severe and symptomatic, is associated with high mortality. The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common underlying disorder in hospitalised patients with euvolaemic hyponatraemia and is a complication of many clinical conditions and drug therapies.We discuss the cases of two patients...

ea0050ep043 | Clinical Biochemistry | SFEBES2017

A Case of Hypoglycaemia

Walsh Sean , Giritharan Sumi , Robinson Adam

We present this 62-year-old man with a background of Marfan’s Syndrome, aortic valve replacement, atrial fibrillation and asthma who presented with increasingly severe episodic hypoglycaemia over a period of 22 years. Of note he was not diabetic and was not on any hypoglycaemia-inducing medications. Extensive investigations included the following: 72 hr fast, 5 hr OGTT, continuous glucose monitoring, basic biochemistry, hormone profiles (GH, LH...

ea0050ep044 | Clinical Biochemistry | SFEBES2017

Investigating an isolated serum alkaline phosphatase: an incidental mediastinal seminoma

Avari Parizad , Shapriya Kavita , Rustin Gordon , Pokrajac Ana

Serum alkaline phophatase (ALP) may be released from various sources, including liver, bone, thyroid, intestine and placenta. Herein, we describe a rare case of an isolated serum ALP rise initially dismissed, and later resulting in an incidental finding of a mediastinal seminoma.A 56-year-old gentleman was referred to the Endocrinology Outpatients by his general practitioner, with a 1-month history of presumed post-viral fatig...

ea0050ep045 | Clinical Biochemistry | SFEBES2017

A curious case of recurrent episodes of multiple-electrolytes derangement

Htun Kyaw Z , Rajkanna Jeyanthy , Sagi Satyanarayana V , Oyibo Samson O

Introduction: Single-electrolyte derangement is a common biochemical finding. Multiple-electrolytes derangement is less common and require multiple and simultaneous corrective therapies. We present a patient who had multiple admissions with multiple-electrolytes derangement, which after further evaluation required a single therapeutic intervention.Case: A 26-year-old lady had eight admissions over three years with abdominal pain and vomiting. During each...

ea0050ep046 | Clinical Biochemistry | SFEBES2017

Blood glucose control in a pregnant female with Type 1 diabetes and Medium-chain acyl-CoA dehydrogenase deficiency (MCADD)

Wilson Debbie , Brown Alison , Gumma Aparna D , Oyibo Samson O

Background: Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is an autosomal recessive inherited disorder resulting in the inability to breakdown medium-chain fatty acids to provide energy during periods of low-calorie intake and hypoglycaemia (infections, fasting, vomiting). Without urgent treatment, the accumulation of toxic fatty acids leads to encephalopathy and sudden death.Pregnant females with Type 1 diabetes requ...

ea0050ep047 | Clinical Biochemistry | SFEBES2017

A rare metabolic condition presenting to Ophthalmology

Macauley Mavin , De-Alwis Nimantha , Joshi Ashwin

Homocystinuria is a rare autosomal recessive disorder of the transsulfuration or methylation pathway in methionine metabolism.We present a case of a 25 years old female, who presented with rapid onset loss of vision in both eyes and short-sightedness. She had a background of well-controlled epilepsy, normal mental and physical development. She had no family history of Marfan’s syndrome.On examinatio...

ea0050ep048 | Clinical Biochemistry | SFEBES2017

Pre-eclampsia as a rare cause of severe hyponatraemia

Seejore Khyatisha , Mighell Amal , Dawson Alison J.

Background: Hyponatraemia is the commonest electrolyte abnormality. It carries a mortality rate of above 50% when plasma sodium concentration falls below 115 mmol/L. We present a case of severe hyponatraemia complicating pre-eclampsia in a primiparous woman.Case Report: A 23-year old healthy primigravida was admitted at 34 weeks’ gestation following an episode of reduced foetal movements. She was hypertensive (BP 171/98 m...

ea0050ep049 | Clinical Biochemistry | SFEBES2017

‘2’ much of a problem with hypoglycaemia

Sukumar Nithya , Venkataraman Hema , Ayuk John

Background: An 88 year old gentleman was referred to the endocrine team as an inpatient with recurrent episodes of spontaneous hypoglycaemia. These occurred in the early hours of the morning when he was found to be unrousable from sleep. There was no background history of diabetes. He was under the oncology team on this admission with pyrexia post-palliative chemotherapy with trabecitidine. Significant past medical history include metastatic solitar...

ea0050ep050 | Clinical Biochemistry | SFEBES2017

Starvation ketoacidosis – a rare but significant metabolic condition

Nardeosingh Siddarth , Savage Amy , Banerjee Moulinath

Diabetic ketoacidosis and pregnancy related ketoacidosis are the most common forms of ketoacidosis seen in acute medical units. We describe here two rare cases of starvation ketoacidosis.Case 1: 63 years old gentleman with no history of diabetes, presented with persistent vomiting for 48 hours. His admission bloods revealed Serum Bicarbonate of 8, pH 7.19, pCO2 2.7, base excess of -17.8, plasma glucose 5.2 mmol/l and serum alc...

ea0050ep051 | Clinical Biochemistry | SFEBES2017

Primum Non Nocere – the need for appropriate assessment before starting testosterone therapy

Moriarty Maura , Meeran Karim , George Emad

A 41 year old Emirati man was reviewed in January 2016 for hypercholesterolaemia managed on diet alone, but direct questioning revealed gradual onset erectile dysfunction over 2 years, treated by a urologist elsewhere. Initial response to Cialis had waned over 18 months. Testosterone replacement (Nebido) had been initiated in June 2015 on the basis of one low morning total testosterone of 3.89 nmol/L (normal range 8.64 – 29). SHBG and prolactin...