Endocrine Abstracts

Post-surgical hypoparathyroidism is most common cause of hypoparathyroidism develops after accidental damage to or removal of the parathyroid glands during surgery. Heart arrhythmias and fainting, even heart failure is reversible complications of hypoparathyroidism, due to low calcium levels. Long QT (LQT) interval may lead to syncope, cardiac arrest, or sudden death. The goal of hypoparathyrodisms treatment is to relieve symptoms and to normalize levels of calcium and phospho...

Primary hyperparathyroidism (PHPT) predominantly affects the elderly, with a peak incidence between ages 55 and 70. Parathyroid adenoma is the principal cause, representing 80–85% of all cases. The aim of the study to determine the frequency of parathyroid adenoma in elderly with high parathyroid hormone levels.Subjects and methods: We performed a retrospective analysis of 31 (30 female, 1 male) elderly wih high parathyroid hormone levels. The demog...

Introduction: Vitamin D deficiency is very common in our population.It is not clear which is the most effective vitamin D dosing regimen in patients with deficiency.Objective: To compare two vitamin D supplementation regimen in patients with vitamin D deficiency.Material and methods: This is an interventional study: Patients atended in our clinic during May and June 2017 with 25-Hydroxyvitamin D below 30 ng/ml were consecutively se...

Introduction: Parathyroid carcinoma and atypical parathyroid adenoma are among rarely encountered causes of primary hyperparathyroidism. Patients with parathyroid carcinoma often differ from those with atypical parathyroid adenoma or parathyromatosis at the time of presentation because patients with parathyroid carcinoma have more profound hypercalcemia as well as invasive tumors. However, at times, it is difficult to distinguish between these conditions both clinically and by...

Introduction: The general function of vitamin D is to regulate phosphorus-calcium metabolism. Vitamin D takes part in other metabolic processes and it has an impact on body mass and on carbohydrate metabolism. Vitamin D also has an influence on nervous system’ functioning and on immune processes. Vitamin D deficiency increases risk of hyperplasia of the parathyroid glands, primary and secondary hyperparathyroidism and osteoporosis.Objectives: To inv...

Objectives: The aim of this study was to analyze the prevalence of some polymorphisms of the CTR-AluI, VDR-FokI, Col1A1y ER-α genes, (involved in bone metabolism), in our population. And evaluate the association of these polymorphisms with bone mineral density and fracture.Design, Patients, and Setting: We performed an observational prospective study in pre- and postmenopausal ambulatory women (n=72 and n=152, respectively).<p ...