Searchable abstracts of presentations at key conferences in endocrinology
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20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

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ECE 2018, 19 - 22 May 2018; Barcelona, Spain

Guided Posters

Diabetes Epidemiology

ea0056gp82 | Diabetes Epidemiology | ECE2018

Maternal exposure to air pollutants and risk of gestational diabetes mellitus in Taiwan

Shen Hsiu-Nien , Hua Sheng-Yuan , Chiu Chang-Ta , Li Chung-Yi

Objective: Mounting evidence has shown an increased risk of gestational diabetes mellitus (GDM) in association with elevated exposure to air pollution. However, limited evidence is available concerning the effect of specific air pollutant(s) on GDM incidence.Methods: We conducted this case-control study on 6717 mothers with GDM diagnosed in 2006–2013 and 6717 age- and year of delivery-matched controls to further address the risk of GDM in relation t...

ea0056gp83 | Diabetes Epidemiology | ECE2018

Prevalence and predictors of gestational diabetes mellitus: a nationwide multicenter prospective study

Aydin Hasan , Celik Ozlem , Yazici Dilek , Altunok Cigdem , Tarcin Ozlem , Deyneli Oguzhan , Sancak Seda , Kiyici Sinem , Aydin Kadriye , Yildiz Bulent Okan

Aim: Gestational diabetes mellitus (GDM) is an important public health issue associated with significant short- and long-term morbidity both for mother and offspring. Prevalence rates of GDM show considerable variation among different countries and regions of the world. The primary aim of this study was to determine the nationwide prevalence and predictors of GDM in Turkey.Materials and methods: We conducted a prospective nationwide screening among pregn...

ea0056gp84 | Diabetes Epidemiology | ECE2018

Incretin hormones in pathogenesis of secondary hyperglycaemia in patients with Cushing’s disease and acromegaly

Machekhina Lubov , Shestakova Ekaterina , Astafieva Lyudmila , Shestakova Marina

Aim of the study: To analyze the dynamics and levels of incretins and neuropeptides secretion in patients with CD and acromegaly and therefore to specify the pathogenesis of carbohydrate metabolism disturbances.Methods: Forty-two patients with Cushing disease and acromegaly were included into the study. All patients were newly diagnosed with Cushing disease and acromegaly. Oral glucose tolerance test (OGTT), during which glucose, glucagon, glucagon like ...

ea0056gp85 | Diabetes Epidemiology | ECE2018

Association of glucagon-to-insulin ratio and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

Mok Ji Oh , Jung Chan Hee , Lee Ki Young

Objective: Although the importance of islet α-cell dysfunction in the pathogenesis of type 2 diabetes has been reappraised, data on whether increase or decrease of glucagon relative to insulin is related with glucose metabolism parameters or metabolic diseases such as nonalcoholic fatty liver disease(NAFLD) in clinical settings are very limited. Therefore, we investigated the association between glucagon-to-insulin ratio(G/I ratio) and presence of NAFLD and metabolic para...

ea0056gp86 | Diabetes Epidemiology | ECE2018

Heart rate variability is related to concomitant glucose fluctuation in longstanding type 1 diabetes

Shalimova Anna , Graff Beata , Szyndler Anna , Wolf Jacek , Blaszkowska Magdalena , Orlowska-Kunikowska Elzbieta , Wolnik Bogumil , Narkiewicz Krzysztof

The presence of type 1 diabetes (DM1) affects the heart rate variability (HRV). However, there are conflicting data on the impact of hyper- and hypoglycaemia on the parameters of cardiovascular autonomic regulation.The aim: To investigate the possible association of glucose fluctuation with HRV in longstanding DM1.Design and methods: We examined 49 patients with longstanding (>20 years) history of DM1 (without overt cardiovascu...

ea0056gp87 | Diabetes Epidemiology | ECE2018

Differential expression of apoptotic and low grade inflammatory markers in Alzheimer’s disease compared to diabetes mellitus type 1 and 2

Alexandraki Krystallenia , Apostolopoulos Nikolaos , Adamopoulos Christos , Stamouli Evangelia , Dalagiorgou Georgia , Papaioannou Theodoros , Analitis Antonios , Karamanou Marianna , Makrilakis Konstantinos , Politis Antonios , Piperi Christina

Objective: Neuroinflammation is a common primary or secondary mediator of the neurodegenerative process accompanying Alzheimer’s disease (AD). Impaired brain insulin signaling, defining brain insulin resistance may represent a link between AD and type 2 diabetes mellitus (T2DM) while neuronal apoptosis may also be involved in the inflammatory process. Peripheral cytokine levels of IL-1β, IL-6, TNFα along with high sensitivity C-reactive protein (hsCRP) and apopt...

ea0056gp88 | Diabetes Epidemiology | ECE2018

Gestational diabetes mellitus and continuous glucose monitoring system. A prospective study.

Marquez-Pardo Rosa , Baena-Nieto Maria-Gloria , Garcia-Garcia-Doncel Lourdes , Cruzado-Begines Concepcion , Torres-Barea Isabel-Maria

Introduction: Gestational diabetes mellitus (GDM) is associated with an increase of maternal-fetal complications. Continuous glucose monitoring system (CGMS) detects postprandial hyperglycemia and hypoglycemia during 24h.Methods: Women with GDM in gestational weeks 26–32 were allocated a CGMS (IproTM2) after diagnosis in an observational prospective study. It was analysed: Mean glucose and standard deviation, area under the curve (AUC) wi...

ea0056gp89 | Diabetes Epidemiology | ECE2018

Depression screening in adults with diabetes

Demirci Ibrahim , Haymana Cem , Sonmez Yusuf Alper , Bolu Abdullah , Kirnap Nazli Gulsoy , Demir Orhan , Dinc Mustafa , Meric Coskun , Aydogdu Aydogan , Azal Omer

Introduction: Elevated depressive symptoms and depressive disorders affect one in four patients with type 1 or type 2 diabetes (1). Thus, routine screening for depressive symptoms is indicated in this high-risk population. Current guidelines all recommend screening for depression in diabetic population(2). The Patient Health Questionnaire-9 (PHQ-9) is a valid screening tool for depression in individuals with diabetes (3). There is no specific data about the prevalence of depre...

ea0056gp90 | Diabetes Epidemiology | ECE2018

Nutritional composition of carbohydrate-rich gluten free products and glycemic index calculation of commercially available gluten free pasta

Koureta Anastasia , Boumpa Apostolia , Tzallas Christos , Themeli Eleni , Tigas Stelios

Background: Celiac disease (CD) is an autoimmune enteropathy triggered by gluten ingestion in genetically susceptible individuals. Its prevalence is ~7 times higher in type 1 diabetes (T1D) patients compared to the general population; in addition to adherence to a gluten free (GF) diet, these patients use carbohydrate counting to estimate their pre-meal insulin dosages. We aimed to (a) compare the nutritional composition between some GF and non GF carbohydrate-rich products av...

ea0056gp91 | Diabetes Epidemiology | ECE2018

Analysis of health-related quality of life in patients with type 2 diabetes mellitus: results of an epidemiological study FORSIGHT-T2DM

Kalashnikova Marina , Gerasimov Andrei , Belousov Dmitriy , Aboishava Lizaveta , Dedov Ivan

Background: The aim of this study was to assess health-related quality of life (HRQoL) of patients living in cities and towns with different population in the Russian Federation (RF) using EQ-5D questionnaire, to calculate health utility index (QALY) and cost-utility ratio (CUR).Methods: One of the goals of the multicenter, observational, epidemiologic study FORSIGHT-DM2 was to evaluate HRQoL using the EQ-5D Questionnaire. The study included more than 20...

ea0056gp92 | Diabetes Epidemiology | ECE2018

Gestational Diabetes Mellitus is associated with increased risk of Non-Alcoholic Fatty Liver Disease: A population-based cohort study

Lavrentaki Aikaterini , Subramanian Anuradhaa , Thomas G Neil , Valsamakis George , Toulis Konstantinos , Daly Barbara , Mastorakos George , Tahrani Abd , Nirantharakumar Krishnarajah

Background: Gestational diabetes mellitus (GDM) is associated with adverse perinatal outcomes, and increased risk of post-natal type 2 diabetes and cardiovascular disease. However, whether GDM increases the risk of developing incident Non-alcoholic Fatty Liver Disease (NAFLD) is unclear and has not been well examined in previous studies. This is important considering the significant health burden of NAFLD and the opportunity to interfere in high risk population in order to red...