Searchable abstracts of presentations at key conferences in endocrinology
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20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

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ECE 2018, 19 - 22 May 2018; Barcelona, Spain

Plenary Lectures

The link between insulin and fatty liver

ea0056pl5 | The link between insulin and fatty liver | ECE2018

The link between insulin and fatty liver

Shulman Gerald

Ectopic lipid deposition in liver and skeletal muscle plays a major role in the pathogenesis of insulin resistance and type 2 diabetes (T2D). Furthermore, nonalcoholic fatty liver disease (NAFLD) is a major predisposing factor for nonalcoholic steatohepatitis (NASH) and hepatocellular cancer and is an independent risk factor of cardiovascular disease. Understanding the cellular and molecular mechanisms by which ectopic lipid promotes insulin resistance in liver and identifying...