ea0056p680 | Steroid metabolism + action | ECE2018
, Das Samir
, Wahala Kristiina
, Van Petegem Filip
, Hammond Geoffrey
Sex Hormone binding globulin (SHBG) is a plasma steroid binding protein that is the major determinant androgen and estrogen access to target tissues. Several ligands of SHBG have been predicted by computational methods or discovered through basic research, they include pharmaceutical, natural plant extracts and anthropogenic endocrine disrupting compounds. In this study we characterized 3,4-Divanillyltetrahydrofuran (DVT), a non-steroidal ligand of SHBG, and Danazol, a synthet...