Endocrine Abstracts

Introduction: Nodular thyroid disease (NTD) is one of the commonest endocrine disease with incidence ranging from 5–30% in various populations Worldwide. They often require surgery for indications such as pressure symptoms or size related reasons. The natural history and etiopathogenesis are largely unclear except in few endemic regions. Immunomodulatory role has often been implicated in their pathogenesis. In this context, we set out study the association between Pro- in...

Thyroid hormones (TH) of maternal origin are critical for the proper fetal development, especially during early pregnancy. Even minor changes in maternal TH circulation can lead to various adverse outcomes. Recent studies found that the metabolites of thyroxine (T4) also play an important physiological role. For example, 3,5-diiodo-L-thyronine (T2) and 3,3′-diiodo-L-thyronine (rT2) can suppress the thyroid stimulating hormone (TSH) level ...