Searchable abstracts of presentations at key conferences in endocrinology
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20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

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ECE 2018, 19 - 22 May 2018; Barcelona, Spain

Symposia

Hot topics in NETs

ea0056s10.1 | Hot topics in NETs | ECE2018

Whole genome landscape in pancreatic neuroendocrine tumours

Corbo Vincenzo

Pancreatic NETs (PanNETs) are characterized by recurrent molecular alterations, including genetic inactivation of MEN1, ATRX/DAXX, and activation of the PI3K/mTOR pathway. The International Cancer Genome Consortium effort on PanNETs provide a first snapshot of how heterogeneous is the combination of genetic alterations that drive this tumour type, yet converging into four pathways whose alteration has been enriched by newly discovered mechanisms. Whole-genome sequencing of 102...

ea0056s10.2 | Hot topics in NETs | ECE2018

Abstract unavailable....