Endocrine Abstracts

Post-surgical hypoparathyroidism is most common cause of hypoparathyroidism develops after accidental damage to or removal of the parathyroid glands during surgery. Heart arrhythmias and fainting, even heart failure is reversible complications of hypoparathyroidism, due to low calcium levels. Long QT (LQT) interval may lead to syncope, cardiac arrest, or sudden death. The goal of hypoparathyrodisms treatment is to relieve symptoms and to normalize levels of calcium and phosphorus. A treatment regimen includes: oral calcium carbonate tablets, vitamin D and human parathyroid hormone, recombinant. A treatment of LQT interval with Implantable cardioverter-defibrillator (ICD) is prevention and termination of arrhythmias. Goal is to show a patient with post-surgical hypoparathyroidism, severe hypocalcemia, hyperphosphatemia, hypothyroidism, tetany, syncope and LQT interval.

Materials and methods: A case report of 60 years old woman who has developed post-surgical hypoparathyroidism and hypothyreoidism with the consequence hypocalcemia and prolonged QT interval. Preserved renal function.

Conclusion: Hypoparathyroidism is most commonly caused by surgery. Consequences are hypocalcemia,hyperphosphatemia. In our case is 60 years old patient who is not well-controlled on calcium supplements and active forms of vitamin D (ionized Calcium 0.67 mmol/l, phosphorus 1.59 mmol/l, magnesium 0.79 mmol/l, PTH 0.37 pmol/l) with tetany, syncope, arrhythmia with prolonged QT interval. We perform implantation of cardioverter defibrillator to prevent sudden death. In our country is not available Human parathyroid hormone, recombinant.