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Belgian Endocrine Society 2018

BES 2018

Comparison of overnight and 48h low dose dexamethasone suppression tests in volunteers using oral contraceptives

ea0057010 | Comparison of overnight and 48h low dose dexamethasone suppression tests in volunteers using oral contraceptives | BES2018

Comparison of overnight and 48 h low dose dexamethasone suppression tests in volunteers using oral contraceptives

Tiphaine Carton , Elise Mathieu , Fleur Wolff , Bernard Corvilain , Natacha Driessens

Introduction: Measurements of midnight salivary cortisol, 24-hour urinary free cortisol (UFC) and 1mg overnight Dexamethasone (DXM) suppression test (short DST) represent classical first line screening tests to diagnose Cushing syndrome. In women using combined Estrogen–Progestogen contraception, cortisol response during short DST is often decreased, leading to false positive (FP = morning plasma cortisol post-DST > 50 nmol/l).Purpose: The main ...