Endocrine Abstracts

We present a 52-year-old female with a 26-year history of type-2 diabetes mellitus who has been difficult to treat owing to the development of multiple insulin allergies. She initially developed local hyperpigmentation and itchy swellings at the injection sites of her Humulin I in 2016, with similar symptoms occurring when she was switched to NovoRapid. Additionally, she developed one severe, systemic reaction to Humulin I. All insulin treatment was stopped, and she was left s...

A 22-year-old male presented to the Emergency Department with nausea and vomiting. He reported thirst, polyuria, reduced appetite and weight loss. He did not have pre-existing medical conditions and did not take regular medications. On examination, he appeared pale and clammy. He was apyrexial, tachycardic and tachypnoeic with normal blood pressure and oxygen saturation. His chest was clear and abdomen generally tender. A venous blood gas revealed pH 6.94, base excess −2...

Introduction: Diabetes Ketoacidosis, DKA, is a serious condition with significant morbidity and mortality. Most DKA patients are potassium deficient, but present with hyperkalaemia due to severe acidosis and insulin deficiency. Hypokalaemia at presentation of DKA is extremely uncommon.Clinical case: A 25 year old man was admitted with severe DKA as a first presentation of diabetes. His venous pH was 6.97, bicarbonate 3.0 mmol/l, potassium 3.4 mmol/l. He ...