Endocrine Abstracts

Endogenous glucocorticoids help to mobilize energy to prepare for daily activity and to deal with stressors, e.g. by catabolic effects on muscle and stimulation of the release of glucose and fat from the liver. Chronic overexposure to glucocorticoids has strong deleterious effects, in medical glucocorticoid and in Cushing’s disease. It is less clear to what extent glucocorticoid signalling may be used as a therapeutic target in the much more frequent consequences of the m...