Endocrine Abstracts

The initial report of the syndrome of Inappropriate Antidiuresis (SIAD) was published as recently as 1960 in the American Journal of Medicine. Schwartz and colleagues described an elegant series of physiological studies, in which two patients with hyponatraemia and lung carcinoma were shown to have an inability to excrete a water load, and who responded to water restriction with a rise in plasma sodium concentration. They termed this syndrome SIADH; in the 60 years since then,...