Endocrine Abstracts

Constitutional delay is a common presentation to paediatric endocrine clinics. Most are boys who have been at the bottom of the normal range for height during childhood and then started to feel left behind as their peers develop in puberty. There is no agreed cut off age but most boys referred are 13–15 years old. Most boys with delay of puberty are healthy, although there is an association with chronic medical conditions (eg inflammatory bowel disease, juvenile rheumatoi...

Hypogonadotrophic hypogonadism (HH) is the only form of infertility that is directly treatable with hormone replacement, either in the form of gonadotrophin injections, or pulsatile GnRH if the underlying defect is hypothalamic and pituitary function is intact. However, men with HH face a complex and confusing journey to access treatment: misinformed that they are irredeemably infertile, struggling to find a clinician with relevant experience and authorisation to prescribe gon...

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