Endocrine Abstracts

Immunotherapy in neuroendocrine neoplasms (NENs) has been investigating over the years, mainly with interferon-alpha-2b and oncolytic virus, without conclusive results. The new immune checkpoint inhibitors (IC-Is) are in an initial phase of investigation in NENs with no published study so far, apart from Merkel Cell Carcinoma (MCC). For this latter NEN Avelumab has been recently approved by the FDA and EMA in advanced disease irrespective of the line of treatment. From a biolo...