Endocrine Abstracts

Obesity is a chronic relapsing disease with significant adverse implications for current and future health. Whilst guidelines recommend first line treatment with lifestyle interventions that include restriction of energy intake, increased physical activity and behavioural modification, these only demonstrate an average decrease of 3–5% initial body weight over 12 months, and weight regain is common. Bariatric surgery is effective, but is generally only offered to people w...

Non-alcoholic fatty liver disease is a condition characterised by deposition of fat within the liver and can be associated with progressive inflammation and fibrosis (NASH). Up to 30% of the population may have NAFLD and yet only a small proportion will have progressive disease. This means that accurate stratification of at risk patients is required to ensure best use of NHS resource. The talk will describe the diagnostic modalities that can be used to identify patients includ...

The twin epidemics of obesity and type 2 diabetes represent a major challenge to healthcare service provision worldwide. It has long been recognised that, while surgery is effective in treating both conditions, only a tiny proportion of patients who might be eligible can access appropriate services and even fewer actually undergo treatment. Furthermore, there exists a significant treatment gap on the continuum of risk:efficacy between diet and lifestyle and surgical interventi...