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21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

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18-21 May 2019, Lyon, France

Plenary Lectures

Genetic epidemiology of puberty timing and reproductive lifespan (Endorsed by the European Journal of Endocrinology)

ea0063pl2 | Genetic epidemiology of puberty timing and reproductive lifespan (Endorsed by the European Journal of Endocrinology) | ECE2019

Genetic epidemiology of puberty timing and reproductive lifespan

Ong Prof Ken

Background: The timing of puberty varies widely between individual children. Those in the extreme early or late groups present commonly to endocrine clinics. Furthermore, in population studies the continuum in puberty timing is associated with long-term health outcomes, such as obesity, Type 2 diabetes, sex steroid-sensitive cancers and also with the timing of menopause and reproductive lifespan. This timing is highly heritable. Genome-wide association studies (GWAS), which ge...