Endocrine Abstracts

In reproductive pathology, the impact of endocrine disruptor’s on fertility potential declining is well documented; women exposed to pesticides have a risk to affect oocyte maturation and competency because Oocyte quality is a key limiting factor in female fertility which is firstly reflected by morphology feature. Centrally located cytoplasm granulation (CLCG) is one of cytoplasmic dysmoprhisms exhibited by oocytes which could be linked to pesticide exposure with relativ...

Testicular germ cell cancer is the most frequent cancer of the young men with an increasing incidence all over the world. Pathogenesis and reasons of this increase remain unknown but epidemiological and clinical data have suggested that like genital malformations and sperm impairment, it could include developmental and environmental factors, including fetal exposure to environmental endocrine disruptors (EEDs). Several groups including ours have shown that TGCC is estrogen dep...

Three decades ago wildlife findings of intersex, malformations and sex ratio changes in marine species, birds and mammals could be associated to environmental pollution. Public concern arose as to whether this was also a threat to humans as many countries experience an increase i.e. in the prevalence of infertility and obesity. Humans are continuously exposed to small doses of hundreds of EDCs throughout life and we know very little about their combined effects. Over the past ...