Endocrine Abstracts

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The rapidly increasing incidence of T1D worldwide and studies among migrants have shown that environmental factors play an important role in the pathogenesis of T1D. Identification of these risk-modulating factors would offer an excellent opportunity to develop effective strategies for prevention of T1D. Vitamin D is one of the main candidates for protection from type 1 diabetes, although prospective epidemiological studies on the effect of vitamin D exposure during pregnancy,...

The 25-hydroxyvitamin D (25OHD) serum concentration is the marker of vitamin D status. It is measured by immunoanalysis, mostly on automated platforms, or by separative methods such as HPLC or LC/MS-MS. An important inter-method variability has been evidenced some years ago. This has however improved recently thanks to the availability of an international standard and of a reference method (RM), and to the implementation of the Vitamin D Standardization Program (VDSP). Some pr...