ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2019) 63 EP27 | DOI: 10.1530/endoabs.63.EP27

Hypertension during primary hyperparathyroidism

Ben Dorel Kyabaambu Nkenda


Endocrinology, Diabetology and Metabolic Diseases department IBN ROCHD University Hospital, Casablanca, Morocco. Neurosciences and Mental Health Laboratory, Casablanca, Morocco. Faculty of Medicine and Pharmacy-University Hassan II, Casablanca, Morocco.


Introduction: Primary hyperparathyroidism is associated with an increased prevalence of high blood pressure. The objective of our work was to evaluate the prevalence and blood pressure profile in patients with primary hyperparathyroidism.

Methods: Retrospective study conducted at the Department of Endocrinology Diabetology and Metabolic Diseases of the University Hospital of Casablanca for a period of 4 years (2014–2018) including all patients followed up for primary hyperparathyroidism.

Results: 25 patients were followed during this period for hyperparathyroidism. The average age was 56.7 years (34–76) with a clear female predominance (84%). 10 had arterial hypertension a prevalence of 40% with an average duration of evolution of 3.75 years. It pre-existed before the diagnosis of hyperparathyroidism. It was moderate in the majority of cases with an average tension of 14/10 cmHg. One patient was on dual therapy, another did not observe treatment and the rest monotherapy. They were all dyspnea on exercise and two patients had cardiac arrhythmias on the electrocardiogram, cardiac echocardiography showed good left ventricular function, one patient had ischemic cardiomyopathy and another had dilatation of the ascending aorta. No ocular repercussions were observed in our cohort and 50% with a moderate insufficiency with an average GFR of 70 ml/min, one patient had already had a cerebrovascular accident.

Conclusion: During primary hyperparathyroidism, hypertension appears moderate, rare complications and balanced tension monotherapy. Our work emphasizes the interest of systematically screening for blood pressure disorders, especially arterial hypertension, in affected individuals.

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