ECE2019 ePoster Presentations Diabetes, Obesity and Metabolism (42 abstracts)
Side effects of topical corticosteroids in the treatment of psoriasis: a case report
Diana Šimonienė 1, , Ieva Auglytė 2 & Simona Liolytė 2
1Hospital of Lithuanian University of Health Sciences, Department of Endocrinology, Kaunas, Lithuania; 2Lithuanian University of Health Sciences (LUHS), Department of Endocrinology, Kaunas, Lithuania.
Using topical corticosteroids, severe adverse reactions occur very rarely, especially - adrenal insufficiency. We describe the case of a patient who presented adrenal insufficiency using topical GCC. 28 y/o female with a history of mild form psoriasis was treated with topical GCC (DERMOVATE) for about 12 years. Thinned skin, translucent vascular-network all over the body (~6 years), weight gain (+10 kg/12 months) and spontaneous haematomas appeared within the time and progressed. The patient was clinically diagnosed with adernal insufficiency syndrome. Topical steroids were discontinued and she received a daily dose of 15 mg to 20 mg hydrocortisone. After three months, a dose of hydrocortisone was reduced. Exogenous glucocorticoids even in topical form have suppressive effects on hypothalamic cortisol releasing hormone and pituitary adrenocorticotropic hormone.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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