ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2019) 63 EP68 | DOI: 10.1530/endoabs.63.EP68

Lack of definite association of vitamin D deficiency with diabetic neuropathy: Investigation in Greek and in Bangladeshi patients

Georgios Papadakis1, Thomas Zambelis2, Panagiotis Kokotis2 & Nikolaos Karandreas2

1STEPS Stoffwechselzentrum, Biel/Bienne, Switzerland; 2Aeginition Hospital, Athens, Greece.

Aim: Determination of the 25(OH) vitamin D levels in Greek-born and in Bangladeshi immigrant patients in Greece with diabetes with and without polyneuropathy.

Materials and methods: The method for the detection and staging of polyneuropathy proposed by Dyck, 1988 was used.

Results: A total of 111 Bangladeshi immigrants and 101 Greek diabetic patients took part in the study. Vitamin D levels were significantly lower in Bangladeshi than in Greek diabetic patients, and were significantly lower in Greek patients with small-fiber neuropathy. In Bangladeshi patients, there was no statistically significant difference in the subgroup of patients with polyneuropathy in comparison to those without polyneuropathy.

Conclusion: The association of vitamin D deficiency only with a small number of Greek patients with exclusively small-fiber neuropathy does not allow us to draw a definite conclusion on the role of vitamin D in the pathogenesis of diabetic neuropathy.

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