ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2019) 63 P727 | DOI: 10.1530/endoabs.63.P727

Is idiopathic mild hyperprolactinemia a cardiovascular risk factor?

Arzu Or Koca1,2,3,4


1Murat, Dağdeviren, Turkey; 2Tolga, Akkan, Turkey; 3Müge, Keskin, Turkey; 4Mustafa, Altay, Uruguay.


Aim: In our study, we aimed at investigating cardiovascular risk predictability by conducting arterial stiffness measurement in patients with idiopathic hyperprolactinemia.

Material – Method: The biochemical parameters and arterial stiffness analyses of 54 patients with idiopathic hyperprolactinemia, who had applied to our polyclinic in 2017 and 2018, and 55 healthy volunteers having similar characteristics with regard to age, sex and body mass index.

Findings: The median prolactin level of the idiopathic hyperprolactinemia patients with a median age of 31 was found 45 ng/mL. The periphery and central blood pressures and pulse wave velocities (PWV) of both the patient group and the control group were found similar. Any relations between prolactin levels and blood pressure and arterial stiffness could not be found.

Conclusion: Our study showed that arterial stiffness did not increase in young patients with idiopathic mild hyperprolactinemia. However, the long-term effects of this mildly elevated prolactin are not known. Prospective randomized studies are required, that could reveal more clearly the prolactin-cardiovascular risk relation, and the clinical effects of extra-pituitary hyperprolactinemia.

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