Aims: To evaluate the prevalence of antinuclear antibodies (ANA) in patients with chronic autoimmune thyroiditis (CAT) associated with periodontal disease (P.D).
Material and methods: 42 patients with TCA and BP were tested for ANA (Group 1) and 50 patients with TCA without BP (Group 2). Inclusion criterias absence of other autoimmune diseases associated with positive ANA patients. Thyroid hormone deficiency has established thyroid function. Patients with B.P were differentiated: initial lesion - gingivitis, aggravated lesion - loss of dental attachment/endodontic lesions.
Results: Incidence of ANA: Group 136 (85.7%), Group 215 (30%). ANA/PD distribution initial lesions 10 (23.8%), advanced lesions 26 (32%). ANA distribution/thyroid function: hypothyroidism 21 (50%); normothyroid 4 (9.5%), thyrotoxicosis 11 (27%). Hypothyroidism associated to PD: inward lesions 3 (30%); advanced lesions 17 (5.3%).
Conclusions: There may be common pathogenic mechanisms for TCA and PD. Hypothyroidism produces an intensified lesional effect at periodontal level.
18 - 21 May 2019
European Society of Endocrinology