Endocrine Abstracts

Background: Bone turnover markers are used in research and clinical practice, but only in part reflect bone formation and resorption. Components of the Wnt-signaling pathway, regulating osteoblastogenesis and osteoblast function, can be measured in serum, however it is unclear whether they reflect underlying bone mass and metabolism.Objective: Determine whether serum levels of Wnt-signalling components reflect bone mass or metabolism in men during growth...