Endocrine Abstracts

Introduction: Obesity is a global problem and its prevalence is on the rise in the U.K. It is associated with multiple co-morbidities with high mortality and has significant impact on healthcare costs. Bariatric surgery in recent past has revolutionized obesity treatment.

Aims: To assess effectiveness of bariatric surgery in terms of metabolic outcomes in patients with obesity in a single center in the UK.

Methods: Retrospective analysis of data was carried out from the medical records and laboratory database for all the patients with obesity who underwent bariatric surgery at Royal Berkshire Hospital from September 2016 until December 2017. Mean weight, BMI, HbA1C, Cholesterol, ALT, Vitamin B12, Folate and vitamin D levels were obtained at baseline pre-op and 1 year following surgery along with co-morbidities like diabetes, hypercholesterolemia, hypertension and sleep apnea.

Results: Patient data were collected from 120 patients (Mean Age 48.03±9.59 years, Male 20.8%, Female 79.2%). 90% of surgeries were laparoscopic Roux-en-Y gastric bypass. Mean Follow up was 12.87±2.65 months. Initial mean MDT weight was 135.77±23.92 kgs which dropped to 124.37±21.92 following induction into bariatric pathway to 90.11±1.05 kgs post-operatively. Initial mean BMI reported as 48.36±6.92 dropped to 32±5.32 with post op EWL 68.46%±19.62. HbA1c improved from baseline of 49.15±17.52 to 35.42±10.25 1 year post-operatively. Significant improvement with respect to all laboratory parameters and co-morbidities were observed post operatively with P-value <0.05.

Conclusion: Bariatric surgery is an effective treatment for obesity and is associated with improvement of laboratory parameters and as a result, alleviation of metabolic syndrome. There is a need to educate people more regarding the effectiveness of the bariatric surgery.